Oshima Tadayuki Department
Specialty Division
, Clinical Medicine Seminars
Position
■ Journal
1.
Introduction
Carcinogenesis of Barrett's esophagus: a review of the clinical literature 2013
2.
Original article
Use of scintigraphy to evaluate gastric accommodation and emptying: comparison with barostat. 2013/01
3.
Original article
REG Iα is a biomarker for predicting response to chemotherapy with S-1 plus cisplatin in patients with unresectable stage IV gastric cancer. 2013/02
4.
Original article
Effect of age and correlation between esophageal visceral chemosensitivity and mechanosensitivity in healthy Japanese subjects. 2013/03
5.
Original article
Histology of symptomatic gastroesophageal reflux disease: is it predictive of response to proton pump inhibitors? 2013/03
6.
Original article
Prostaglandin E(2) mediates acid-induced heartburn in healthy volunteers. 2013/03
7.
Original article
Acidic deoxycholic acid and chenodeoxycholic acid induce interleukin-8 production through p38 mitogen-activated protein kinase and protein kinase A in a squamous epithelial model. 2013/05
8.
Case report
Successful Self-Expandable Metallic Stent Placement for a Case of Distal Rectal Stenosis due to Gastric Cancer Metastasis. 2013/05
9.
Original article
Clinical outcomes and risk factors for perforation in gastric endoscopic submucosal dissection: A prospective pilot study. 2013/06
10.
Original article
Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front. 2013/10
11.
Original article
Multi-center randomized controlled study to establish the standard third-line regimen for Helicobacter pylori eradication in Japan. 2013/10
12.
Original article
IL-4 induces columnar like differentiation of esophageal squamous epithelium through JAK/PI3K pathway: possible role in pathogenesis of Barrett's esophagus. 2014/02
13.
Original article
A Randomized, Double-Blind, Placebo-Controlled Study of Rebamipide for Gastric Mucosal Injury Taking Aspirin With or Without Clopidogrel. 2014/03
14.
Original article
Effect of Rikkunshito on the expression of substance P and CGRP in dorsal root ganglion neurons and voluntary movement in rats with experimental reflux esophagitis 2014/04
15.
Original article
Helicobactor pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development 2014/05
16.
Introduction
[Gastrointestinal motility disorders of functional dyspepsia]. 2014/06
17.
Introduction
Gastrointestinal motility disorders of functional dyspepsia. 2014/06
18.
Original article
IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling. 2014/06
19.
Original article
Evaluation of Discomfort During Colonoscopy with Conventional and Ultrathin Colonoscopes in Ulcerative Colitis Patients. 2014/07
20.
Original article
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel. 2014/08
21.
Original article
Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis. 2014/08
22.
Original article
Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis. 2014/08
23.
Case report
Asymptomatic Free Air Caused by Mallory-Weiss Tears during Endoscopy 2015
24.
Original article
FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. 2015
25.
Original article
Evaluation of discomfort during colonoscopy with conventional and ultrathin colonoscopes in ulcerative colitis patients. 2015/01
26.
Original article
Evidence-based clinical practice guidelines for functional dyspepsia. 2015/01
27.
Original article
The effects of 5-hydroxytryptamine1a receptor agonist, buspirone on the gastric fundus accommodation in an animal model using guinea pigs. 2015/02
28.
Original article
The effects of 5-hydroxytryptamine1a receptor agonist, buspirone on the gastric fundus accommodation in an animal model using guinea pigs. 2015/04
29.
Original article
Effect of REG Iα protein on angiogenesis in gastric cancer tissues. 2015/05
30.
Original article
Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin. 2015/05
31.
Introduction
[Role of acid in functional dyspepsia]. 2015/07
32.
Introduction
[The effect of antianxiety and anti-depressive agents for the acid-related gastrointestinal diseases]. 2015/07
33.
Original article
Childhood abuse history is associated with the development of dyspepsia: a population-based survey in Japan. 2015/07
34.
Original article
Epidemiology of Functional Gastrointestinal Disorders in Japan and in the World. 2015/07
35.
Original article
Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer. 2015/07
36.
Original article
The Nonsteroidal Anti-inflammatory Drug Diclofenac Reduces Acid-Induced Heartburn Symptoms in Healthy Volunteers. 2015/07
37.
Introduction
PAR-2 activation enhances weak acid-induced ATP release through TRPV1 and ASICs sensitization in human esophageal epithelial cells. 2015/08
38.
Original article
Diagnosis of small intramucosal signet ring cell carcinoma of the stomach by non-magnifying narrow-band imaging: A pilot study. 2015/09
39.
Original article
Morphological Characteristics of Early Gastric Neoplasms Detected After Helicobacter pylori Eradication. 2015/09
40.
Introduction
Validity and Reliability of the Japanese Version of the Rome III Diagnostic Questionnaire for Irritable Bowel Syndrome and Functional Dyspepsia. 2015/09
41.
Introduction
Histological diagnosis of gastric submucosal tumors: A pilot study of endoscopic ultrasonography-guided fine-needle aspiration biopsy vs mucosal cutting biopsy. 2015/10
42.
Original article
Impairment of gastric accommodation induced by water-avoidance stress is mediated by 5-HT2B receptors. 2016/02
43.
Original article
Irritable bowel syndrome: What physicians should know? 2016/02
44.
Case report
[Case Report; A case of esophageal achalasia diagnosed with HRM]. 2016/03
45.
Case report
Efficacy of Intrathecal MTX/Ara-C Combined with Systemic Chemotherapy in a Gastric Cancer Patient with Meningeal Carcinomatosis. 2016/03
46.
Case report
Efficacy of Intrathecal MTX/Ara-C Combined with Systemic Chemotherapy in a Gastric Cancer Patient with Meningeal Carcinomatosis. 2016/03
47.
Original article
Interferon γ-Induced Nuclear Interleukin-33 Potentiates the Release of Esophageal Epithelial Derived Cytokines. 2016/03
48.
Original article
Serotonin disrupts esophageal mucosal integrity: an investigation using a stratified squamous epithelial model. 2016/03
49.
Original article
Gastrointestinal mucosal barrier function and diseases. 2016/04
50.
Original article
Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn. 2016/05
51.
Original article
Gastroesophageal reflux disease-related and functional heartburn: pathophysiology and treatment. 2016/05
52.
Original article
Localization of specialized intestinal metaplasia and the molecular alterations in Barrett esophagus in a Japanese population: an analysis of biopsy samples based on the"Seattle"biopsy protocol. 2016/05
53.
Original article
Prevalence of irritable bowel syndrome - like symptoms in Japanese patients with inactive inflammatory bowel disease. 2016/05
54.
Original article
Morphological Characteristics of Early Gastric Neoplasms Detected After Helicobacter pylori Eradication. 2016/06
55.
Introduction
Long journey to prevent metachronous gastric cancer after endoscopic resection 2016/07
56.
Original article
Prevalence and self-recognition of chronic constipation - Internet survey. 2016/07
57.
Original article
Role of regenerating gene I in claudin expression and barrier function in the small intestine. 2016/07
58.
Original article
Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015. 2016/08
59.
Original article
What types of early gastric cancer are indicated for endoscopic ultrasonography staging of invasion depth? 2016/08
60.
Original article
Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin. 2016/09
61.
Original article
Esophageal stricture after endoscopic submucosal dissection treated successfully by temporary stent placement. 2016/09
62.
Original article
Genetic instability, CpG island methylator phenotype, and proliferative activity are distinct differences between diminutive and small tubular adenoma of the colorectum. 2016/10
63.
Original article
Serotonin disrupts esophageal mucosal integrity: an investigation using a stratified squamous epithelial model. 2016/11
64.
Original article
Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients. 2017/03
65.
Original article
Effect of Vonoprazan, a Potassium-Competitive Acid Blocker, on the (13)C-Urea Breath Test in Helicobacter pylori-Positive Patients. 2017/03
Involvement of gut microbiota in association between GLP-1/GLP-1 receptor expression and gastrointestinal motility. 2017/04
68.
Original article
A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia. 2017/05
69.
Original article
Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract. 2017/05
70.
Original article
Adenosine triphosphate induces P2Y2 activation and interleukin-8 release in human esophageal epithelial cells. 2017/07
71.
Original article
Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia. 2017/07
72.
Original article
Are the Symptoms of an NSAID-Induced Ulcer Truly Milder Than Those of an Ordinary Ulcer? 2017/08
73.
Original article
Analysis of risk factors for colonic diverticular bleeding and recurrence. 2017/09
74.
Original article
Involvement of gut microbiota in the association between gastrointestinal motility and 5-HT expression/M2 macrophage abundance in the gastrointestinal tract. 2017/09
75.
Original article
A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial. 2017/10
76.
Original article
Effects of long-term aspirin use on molecular alterations in precancerous gastric mucosa in patients with and without gastric cancer. 2017/10
Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and meta-analysis. 2018/01
79.
Original article
Association between gastrointestinal motility and macrophage/mast cell distribution in mice during the healing stage after DSS-induced colitis 2018/06
80.
Original article
Objective image analysis of non-magnifying image-enhanced endoscopy for diagnosis of small depressed early gastric cancers 2018/07
81.
Original article
Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases. 2018/07
82.
Original article
Effect of probiotic Bifidobacterium bifidum G9-1 on the relationship between gut microbiota profile and stress sensitivity in maternally separated rats. 2018/08
83.
Original article
Filaggrin and tight junction proteins are crucial for IL-13-mediated esophageal barrier dysfunction. 2018/09
84.
Original article
Sex differences in associations among metabolic syndrome, obesity, related biomarkers, and colorectal adenomatous polyp risk in a Japanese population 2018/09
85.
Original article
New Approaches to Diagnosis and Treatment of Functional Dyspepsia 2018/10
86.
Original article
Randomised clinical trial: vonoprazan versus lansoprazole for the initial relief of heartburn in patients with erosive oesophagitis 2018/10
87.
Original article
Colonic M1 macrophage is associated with the prolongation of gastrointestinal motility and obesity in mice treated with vancomycin 2019/01
88.
Original article
Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center. Journal of Gastroenterology 2019/01
89.
Original article
Duodenal low-grade inflammation and expression of tight junction proteins in functional dyspepsia 2019/02
90.
Original article
Alteration of GLP-1/GPR43 expression and gastrointestinal motility in dysbiotic mice treated with vancomycin 2019/03
91.
Original article
Chenodeoxycholic Acid Releases Proinflammatory Cytokines from Small Intestinal Epithelial Cells Through the Farnesoid X Receptor. Digestion 2019/03
92.
Original article
Eosinophil-associated microinflammation in the gastroduodenal tract contributes to gastric hypersensitivity in a rat model of early-life adversity 2020/11
93.
Introduction
A Case of Severe Acute Gastritis as an Immune-Related Adverse Event After Nivolumab Treatment: Endoscopic and Pathological Findings in Nivolumab-Related Gastritis. 2021/07
Differences in esophageal perception between proximal and distal esophagus evaluated by electrical stimulation 2012/10/16
2.
Factors Affecting the Medical Consultation byDyspepsia in Japan 2013/03/02
3.
Relationship between prevalence of IBS-like symptoms and quality of life in Japanese patients with Inactive Inflammatory Bowel disease 2013/03/02
4.
Significant differences between proximal and distal esophagus in initial sensory thresholds and types of reported symptoms induced by electrical stimulation 2013/03/02
5.
Groα promotes invasion of gastric cancer cells 2013/05/18
6.
Childhood physical, sexual and psychological abuse are associated with the development of functional dyspepsia 2013/05/19
7.
5-HT2B receptor is involved in the regulation of gastric accommodation: A lesson from a model of gastric accommodation using conscious guinea pigs 2013/05/20
8.
IBS-like symptoms in Japanese patients with inactive inflammatory bowel disease is associated with decreased quality of life 2013/05/20
9.
TH2 cytokines induce the transdifferentiation of the normal human esophageal squamous cell toward columnar cell: A lesson from a stratified squamous epithelial model 2013/05/20
10.
A randomized double-blind crossover placebo-controlled study to investigate the effect of nonsteroidal anti-inflammatory drug on acid-induced esophageal sensation in healthy volunteers 2013/05/21
11.
Acidic deoxycholic acid and chenodeoxycholic acid induce interleukin-8 production through p38 MAPK and PKA: A lesson from a stratigied squamous esophageal epithelial model 2013/05/21
12.
Both of esophageal visceral chemosensitivity and mechanosensitivity were similar in asymptomatic esophagitis(AE) and healthy subjects and were hypersensitive in non-erosive reflux disease(NERD) 2013/05/21
13.
Cross-sectional study of the association between obesity and barrett's esophagus in a japanese population: A hospital-based prospective pilot study 2013/05/21
14.
Down-regulation of submucosal claudin-18 involved in invasive and proliferative potential of gastric cancer 2013/08/03
15.
Functional dyspepsia: New insight into the pathophysiology and treatment(Invited Speaker) 2013/09/07
16.
Clinical outcomes and risk factors for perforation in gastric ESD:a prospective pilot study 2013/09/22
17.
Expression of Reg family genes in the gastrointestinal tract injured by indomethacin 2013/09/23
18.
Early satiety is a dyspeptic symptom associated with impaired gastric acoomodation in Japanese FD patients 2013/09/24
19.
A typical symptoms and HRQOL of patients with asymptomatic GERD is asymptomatic GERD really silent? 2013/09/27
20.
IL-4 induces columnar differentiation of esophageal squamous epithelium through JAK/PI3K pathway: A possible role in the pathogenesis of barrett's esophagus 2013/09/27
21.
Down-regulation of claudin-1815 associated with proliferative and invasive potential of gastric cancer at the invasive front 2013/10/16
22.
IL-33 in the pathogenesis of gastroesophageal reflux disease 2014/02/15
23.
Serotonin 2B receptor is involved in the stress-induced inhibition of gastric accommodation in conscious guinea pigs 2014/05/03
24.
Intra-venous Corticotropin Releaseing Hormone(CRH) administration increased esophageal electrical sensitivity in normal subjects 2014/05/05
25.
Esophageal epithelial-derived IL33 acts as an exaggerator of inflammation in the pathogenesis of GERD 2014/05/06
26.
Improvement effect of Rikkunshito mediated by sertonin 2B recepter antagonism in inhibition of gastric accommodation 2014/05/06
27.
Junctional adhesion molecule-a is a contributing factor for gastric cancer cell proliferation and invation 2014/05/06
28.
Effects of nizatidine and famotidine on gastric mitility in healthy volunteers -a randomized crossover trial 2014/09/06
29.
Efficacy of serotonin type3 receptor antagonist ramosetron in the treatment of diarrhea-predominant irritable bowel syndrome with inactive Crohn's disease, a pilot trial 2014/09/06
30.
Association between obesity and barrett's esophagus in a Japanese population 2014/09/23
31.
Esophageal epithelial-derived intracellular IL-33 exaggerates inflammation in the pathogenesis of reflux esophagitis 2014/09/23
32.
Childhood Abuse history is associated with the developmant of dyspepsia - a population based survey 2014/10/23
33.
Prevalence and Self-Recognition of Sonstipation in Japanese Population 2015/02/08
34.
Regulation of Esophageal Epithelial-derived Cytokines by IL-33 2015/02/08
35.
New insight into the pathophysiology, of functional dyspepsia : a lesson from a model for measuring gastric accommodation in conscious guinea pigs 2015/04/24
36.
TRPV1 and ASICs exacerbate acid-induced ATP release through PAR-2 activation 2015/04/24
37.
Non-Magnifying Narrow-Band Imaging of Small Intramucosal Signet Ring Cell Carcinoma of the Stomach 2015/05/16
38.
Effect of REG Protein on Mucosal Permeability and Adhesion Molecule Expression in the Small Intestine 2015/05/17
39.
Evaluation of Discomfort During Colonoscopy With a New Ultrathin Flexible Colonoscope in Crohn's Disease. A Randomized Controlled Trial 2015/05/17
40.
Histological Diagnosis of Gastric Submucosal tumors: Endoscopic Ultrasonography-Guided Fine-Needle Aspiration Biopsy vs. Mucosal Cutting Biops 2015/05/18
41.
PAR-2 Activation Enhances Acid-Induced ATP Release Through TRPV1 and ASICs Sensitization in Human Esophageal Epithelial Cells 2015/05/18
42.
Upregulation and the Regulation of Esophageal Epithelial-Derived IL-33 in Non-Erosive Reflux Disease 2015/05/18
Case Series of Laparoscopic Assisted Endoscopic Submucosal Dissection (LAESD) 2015/05/19
45.
Effect of H.pylori infection on GLP-1 expression and gastrointestinal motility 2015/12/05
46.
Possibility of EMR/ESD as a diagnostic therapy for colorectal neoplasms in association with ulcerative colitis 2015/12/05
47.
Upper gastrointestinal symptoms in patients with gastroduodenal ulcers: Use of non-steroidal anti-inflammatory drugs and low-dose aspirin 2015/12/06
48.
Adenosine Triphosphate-Induced Purinergic Receptor Activation and Proinflammatory Cytokine Release in Human Esophageal Epithelial Multilayer Cells 2016/05/22
49.
Involvement of Gut Microbiota in the Association Between Macrophage and Gastrointestinal Motility 2016/05/22
50.
The Role of Serotonin in Reflux-Induced Esophageal Mucosal Injury in Human Esophageal Epithelial Cells 2016/05/22
51.
A Double-Blind Placebo Controlled Study of Acotiamide Hydrochloride for Efficacy on Gastrointestinal Motility of Patients With Functional Dyspepsia 2016/05/23
52.
Is the Symptoms of NSAIDs Ulcer Truly Milder Than That of Ordinary Ulcer? 2016/05/23
53.
Effect of REG Protein on the Link Claudin Expression and Mucosal Permeability in the Small Intestine 2016/05/24
54.
Effect of Vonoprazan, a Potassium-Competitive Acid Blocker, on the 13C Urea Breath Test in H. pylori-Positive Japanese Patients 2016/05/24
55.
Localization of Specialized Intestinal Metaplasia and the Molecular Alterations and Cellular Phenotype in Barrett's Esophagus in a Japanese Population: An Analysis Based on the "Seattle" Biopsy Protocol 2016/05/24
56.
Alteration of gastrointestinal motility and mast cell behavior in mice after DSS-induced colitis 2016/08/26
57.
Diagnostic value of constipation in the Japanese population, using the Rome III criteria and definitions from the Japanese Society of Internal Medicine 2016/08/26
58.
Esophageal epithelial IL-33 is up-regulated in patients with non-erosive reflux disease 2016/08/27
59.
Comparison of molecular alterations and proliferative activity between diminutive and small tubular adenoma of the colorectum 2016/11/03
60.
Comparison of suitability of three snares with various hardness for cold snare polypectomy 2016/11/03
61.
Association between mast cell and gastrointestinal motility in mice after DSS-induced cilitis 2016/11/04
62.
Evalution of the diagnostic performance of colon capsule endoscopy for colon polyps in Hyogo college of Medicine 2016/11/05
63.
The baseline ratio of neutrophils to lymphocytes is associated with outcome of paclitaxel plus ramucirumab treated metastatic or unresectable locally advanced gastric adenocarcinoma 2016/11/05
64.
Prevalence of gastric motility disorders in patients with PDS type functional dyspepsia 2017/03/23
65.
Role of dysmotility in functional dyspepsia and efficacy of acotiamide 2017/03/23
66.
Association between Clostridium difficile infection and acid suppression: A systematic review and meta-analysis 2017/03/24
67.
Effect of gut microbiota on Reg Illr expression in relation to intestinal immunity 2017/03/24
68.
Investigation of esophageal epithelial function using 3D culture system 2017/03/24
69.
Role of gut microbiota on GLP-1 receptor expression and gastrointestinal motility 2017/03/24
70.
Low-grade inflammation and epithelial junctional proteins of duodenal mucosa in functional dyspepsia 2017/03/25
71.
The duodenum, a new target for research 2017/03/25
72.
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel 2017/04/27
73.
Are the symptoms of an NSAIDs-induced ulcer truly milder than those of an ordinary ulcer? 2017/04/27
74.
Involvement of gut microbiota in Reg IIIg expression in the intestinal mucosa 2017/04/28
75.
Involvement of H. pylori infection in PAX6/GLP-1 expression and gastrointestinal motility 2017/04/28
76.
Analysis of Risk Factors for Colonic Diverticular Bleeding and Recurrence. 2017/05/06
77.
Ratio of Neutrophil to Lymphocytes is Useful to Predict the Prognosis of Patients with Paclitaxel Plus Ramucirumab Treatment for Unresectable Advanced Gastric Cancer. 2017/05/06
78.
Associations Among Adiposity, Mediating Biomarkers and Colorectal Adenomatous Polyps Risk in a Japanese Population 2017/05/08
79.
Relationship between Intestinal Motility and Small Intestinal Inflammation after acut E.colitis. 2017/05/08
80.
Upregulation of Esophageal Prostaglandin E2 Levels in Patients with Heartburn. 2017/05/08
81.
Duodenal Low-Grade Inflammation and Tight Junction Proteins in Functional Dyspepsia. 2017/05/09
82.
Magnitude and Nature of Association between Clostridium Difficile Infection and Acid Suppression: A Systematic Literature Review and Meta-Analysis. 2017/05/09
83.
Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia. 2017/05/09
84.
Long-term effects of H. pylori eradication on molecular alterations related to gastric carcinogenesis. 2017/10/31
85.
Antibiotics treatment prolongs gastrointestinal transit time accompanted by increase of colonic GLP-1/GPR43 expression. 2018/06/02
86.
Long-term effects of H. pylori eradication on molecular alterations in precancerous lesions, atrophic mucosa and intestinal metaolasia. 2018/06/02
87.
Double-blind, randomized trial of effects of vonoprazan and lansoprazole for the first seven days on relief of gastroesophageal reflux disease symtopms. 2018/06/03
88.
Combination of neutrophil-to-lymphocyte ratio (NTR) and G8 screening tool is useful to predict overall survival of elderly patients with chemotherapy for unresectable/recurrent gastric cancer. 2018/06/05
89.
A present status of the treatment for constipation before and after the publication of the clinical guidelines of chronic constipation in Japan. 2018/07/05
90.
A randomized double-blind placebo controlled trial on the effect of magnesium oxide in patients with chronic constipation. 2018/07/05
91.
Effect of vancomycin treatment on colonic GLP-1/GRP 43 expression and gastrointestinal transit time. 2018/07/05
92.
Sex differences in associations among metabolic syndrome, obesity, related biomarkers, and colorectal adenomatous polyp risk in a Japanese population. 2018/07/05
93.
Two cases of incidental plasma cell neoplasm: diagnostic roles of EMA and CD79a immunohistochemistry 2021/09/23