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Journal
Presentation
    （Last updated : 2022-03-18 11:01:38）
  Enomoto Hirayuki
   Department   Specialty Division  , Clinical Medicine Seminars
   Position  
■ Journal
1. Introduction　 Hepatoma-derived growth factor(HDGF)in liver disease. 2013
2. Original article　 Interferon-gamma-mediated tissue factor expression contributes to T-cell-mediated hepatitis through induction of hypercoagulation in mice. 2013/01
3. Introduction　 Hepatoma-derived growth factor(HDGF)as a potential target for cancer therapy. 2013/05
4. Original article　 Association of amino acid imbalance with the severity of liver fibrosis and esophageal varices 2013/06 Link
5. Introduction　 Molecular detection of intraperitoneal bacterial infection in cirrhotic ascites. 2013/07
6. Original article　 Glycated albumin to glycated hemoglobin ratio as a biomarker of liver fibrosis. 2014
7. Original article　 Role of hepatoma-derived growth factor in antiangiogenic therapy for hepatocellular carcinoma. 2014
8. Introduction　 Relevance of the Core 70 and IL-28B polymorphism and response-guided therapy of peginterferon alfa-2a ± ribavirin for chronic hepatitis C of Genotype 1b: a multicenter randomized trial, ReGIT-J study. 2014/03 Link
9. Original article　 New malignant grading system for hepatocellular carcinoma using the Sonazoid contrast agent for ultrasonography. 2014/04 Link
10. Introduction　 Regulation of hepatoma-derived growth factor(HDGF) for anti-cancer therapy. 2014/04
11. Introduction　 Diagnosis of Spontaneous Bacterial Peritonitis and an In Situ Hybridization Approach to Detect an "Unidentified" Pathogen. 2014/06 Link
12. Original article　 Hepatitis C virus relapse was suppressed by long-term self-injection of low-dose interferon in patients with chronic hepatitis C after pegylated interferon plus ribavirin treatment. 2014/06 Link
13. Original article　 Treatment Response and Tolerability in Elderly Patients with Chronic Hepatitis C:Subgroup Analysis in ReGIT-J Study. 2014/06 Link
14. Original article　 Hepatitis C virus relapse was suppressed by long-term self-injection of low-dose interferon in patients with chronic hepatitis C after pegylated interferon plus ribavirin treatment. 2014/07
15. Original article　 Nationwide survey in Japan regarding splenectomy/partial splenic embolization for interferon treatment targeting hepatitis C virus-related chronic liver disease in patients with low platelet count 2014/08
16. Original article　 Thrombocytopenia in pegylated interferon and ribavirin combination therapy for chronic hepatitis C. 2014/08 Link
17. Original article　 Serum zinc value in patients with hepatitis virus-related chronic liver disease:association with the histological degree of liver fibrosis and with the severity of varices in compensated cirrhosis. 2014/09 Link
18. Original article　 Clinical significance of pretreatment serum interferon-gamma-inducible protein 10 concentrations in chronic hepatitis C patients treated with telaprevir-based triple therapy. 2014/12 Link
19. Original article　 Two randomized controlled studies comparing the nutritional benefits of branched-chain amino acid (BCAA) granules and a BCAA-enriched nutrient mixture for patients with esophageal varices after endoscopic treatment. 2015/01 Link
20. Original article　 A new metabolism-related index correlates with the degree of liver fibrosis in hepatitis C virus-positive patients. 2015/03
21. Original article　 A new metabolism-related ndex correlates with the degree of liver fibrosis in hepatitis C virus-positive patients. 2015/03
22. Introduction　 Hepatoma-Derived Growth Factor: Its Possible Involvement in the Progression of Hepatocellular Carcinoma. 2015/06 Link
23. Original article　 Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial. 2015/06 Link
24. Introduction　 Liver fibrosis markers of nonalcoholic steatohepatitis. 2015/06 Link
25. Original article　 Development of risky varices in alcoholic cirrhosis with a well-maintained nutritional status. 2015/09 Link
26. Introduction　 Factors associated with the response to intereferon-based antiviral therapies for chronic hepatitis C. 2015/11 Link
27. Original article　 Downregulation of HDGF inhibits the growth of hepatocellular carcinoma cells in vitro and in vivo. 2015/12 Link
28. Original article　 Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry. 2016/01 Link
29. Original article　 B-Cell Activating Factor Belonging to the Tumor Necrosis Factor Family and Inter feron-γ-Inducible Protein-10 in Autoimmune Hepatitis. 2016/03 Link
30. Original article　 Clinical implication of serum Wisteria floribunda Agglutinin-Positive Mac-2-binding protein in treatment naïve chronic hepatitis B. 2016/03 Link
31. Original article　 Relationship Between Hepatic Steatosis and the Elevation of Aminotransferases in HBV-Infected Patients With HBe-Antigen Negativity and a Low Viral Load. 2016/04 Link
32. Original article　 Impact of serum Wisteria floribunda agglutinin positive Mac-2-binding protein and serum interferon-γ-inducible protein-10 in primary biliary cirrhosis 2016/05 Link
33. Original article　 Impact of serum Wisteria floribunda agglutinin positive Mac-2-binding protein and serum interferon-γ-inducible protein-10 in primary biliary cirrhosis. 2016/05 Link
34. Original article　 improvement in the Amino Acid Imbalance in Hepatitis C Virus Infected Patients After Viral Eradication by Interferon Treatment. 2016/05 Link
35. Original article　 Clinical significance of serum Wisteria floribunda agglutinin-positive Mac-2-binding protein level and high sensitivity C reactive protein concentration in autoimmune hepatitis. 2016/06 Link
36. Original article　 Serum hyaluronic acid predicts protein-energy malnutrition in chronic hepatitis C. 2016/07 Link
37. Original article　 A proposed predictive model for advanced fibrosis in patients with chronic hepatitis B and its validation. 2016/08 Link
38. Original article　 A predictive model for carcinogenesis in patients with chronic hepatitis B undergoing entecavir therapy and its validation. 2016/09 Link
39. Original article　 Impact of Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein in Patients with Hepatitis C Virus-Related Compensated Liver Cirrhosis. 2016/09 Link
40. Original article　 Clinical implication of serum Wisteria floribunda agglutinin positive Mac-2-binding protein level on hepatitis B e-antigen loss or seroconversion in hepatitis B e-antigen positive patients. 2016/10 Link
41. Original article　 Clinical significance of serum wisteria floribunda agglutinin-positive Mac-2-binding protein level in non-alcoholic steatohepatitis. 2016/11 Link
42. Original article　 An Increased Ratio of Glycated Albumin to HbA1c Is Associated with the Degree of Liver Fibrosis in Hepatitis B Virus-Positive Patients. 2016/12 Link
43. Original article　 Comparison of sleep disorders in chronic hepatitis C patients treated with interferon-based therapy and direct acting antivirals using actigraphy. 2016/12 Link
44. Original article　 Effect of L-Carnitine in Patients With Liver Cirrhosis on Energy Metabolism Using Indirect Calorimetry: A Pilot Study. 2016/12 Link
45. Original article　 Effects of Helicobacter pylori Eradication on the Platelet Count in Hepatitis C Virus-Infected Patients. 2016/12 Link
46. Original article　 Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein for patients with chronic hepatitis B and C: a comparative study. 2016/12 Link
47. Original article　 Comparison of FIB-4 index and aspartate aminotransferase to platelet ratio index on carcinogenesis in chronic hepatitis B treated with entecavir. 2017/01 Link
48. Original article　 Prediction of development of hepatocellular carcinoma using a new scoring system involving virtual touch quantification in patients with chronic liver diseases. 2017/01 Link
49. Original article　 Prognostic significance of nonprotein respiratory quotient in patients with liver cirrhosis. 2017/01 Link
50. Original article　 Predictive factors in patients with hepatocellular carcinoma receiving sorafenib therapy using time-dependent receiver operating characteristic analysis. 2017/02 Link
51. Original article　 Proposal of a predictive model for advanced fibrosis containing Wisteria floribunda agglutinin-po
sitive Mac-2-binding protein in chronic hepatitis C. 2017/03 Link
52. Introduction　 Similarities and Differences in Autoimmune Hepatitis Epidemiology between East and West: Autoimmune Hepatitis in East Asia, Southeast Asia, and South Asia 2017/04 Link
53. Original article　 Effect of psoas muscle mass after endoscopic therapy for patients with esophageal varices. 2017/05 Link
54. Original article　 Changes in skeletal muscle mass after endoscopic treatment in patients with esophageal varices. 2017/06 Link
55. Original article　 Clinical utility of bioimpedance analysis in liver cirrhosis. 2017/06 Link
56. Original article　 Comparison of Prognostic Impact between the Child-Pugh Score and Skeletal Muscle Mass for Patients with Liver Cirrhosis. 2017/06 Link
57. Original article　 Comparison of Prognostic Impact between the Child-Pugh Score and Skeletal Muscle Mass for Patients with Liver Cirrhosis. 2017/06
58. Other　 Effect of dexmedetomidine in the prophylactic endoscopic injection sclerotherapy for oesophageal varices: a study protocol for prospective interventional study. 2017/06 Link
59. Original article　 Impact of Virtual Touch Quantification in Acoustic Radiation Force Impulse for Skeletal Muscle Mass Loss in Chronic Liver Diseases. 2017/06 Link
60. Original article　 Implication of Psoas Muscle Index on Survival for Hepatocellular Carcinoma Undergoing Radiofrequency Ablation Therapy. 2017/06 Link
61. Original article　 Prognostic significance of sarcopenia in patients with hepatocellular carcinoma undergoing sorafenib therapy. 2017/08 Link
62. Other　 Effect of nalfurafine hydrochloride in patients with chronic liver disease with refractory pruritus on sleep disorders: a study protocol for single-arm, prospective, interventional study. 2017/09 Link
63. Other　 Efficacy of capsule endoscopy in patients with cirrhosis for the diagnosis of upper gastrointestinal lesions and small bowel abnormalities: a study protocol for prospective interventional study. 2017/09 Link
64. Original article　 The in vivo antitumor effects of type I-interferon against hepatocellular carcinoma: the suppression of tumor cell growth and angiogenesis. 2017/09 Link
65. Original article　 Predictors Associated with Increase in Skeletal Muscle Mass after Sustained Virological Response in Chronic Hepatitis C Treated with Direct Acting Antivirals. 2017/10 Link
66. Original article　 Development of a simple predictive model for decreased skeletal muscle mass in patients with compensated chronic liver disease. 2017/11 Link
67. Original article　 Effect of pretreatment psoas muscle mass on survival for patients with unresectable pancreatic cancer undergoing systemic chemotherapy. 2017/11 Link
68. Original article　 Prognostic significance of low skeletal muscle mass compared with protein-energy malnutrition in liver cirrhosis. 2017/11 Link
69. Other　 Effect of physical exercise on sarcopaenia in patients with overt hepatic encephalopathy: a study protocol for a randomised controlled trial. 2017/12 Link
70. Original article　 Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis. 2017/12 Link
71. Original article　 Relationship between skeletal muscle mass and liver fibrosis markers for patients with hepatitis C virus related liver disease. 2017/12 Link
72. Other　 Clinical impact of physical exercise on sleep disorder as assessed by actigram in patients with chronic pancreatitis: a study protocol for a randomised controlled trial. 2018/02 Link
73. Other　 Effect of exercise therapy on sarcopenia in pancreatic cancer: a study protocol for a randomised controlled trial. 2018/02 Link
74. Other　 Implication of exercise interventions on sleep disturbance in patients with pancreatic cancer: a study protocol for a randomised controlled trial. 2018/02 Link
75. Original article　 Changes in liver stiffness and steatosis among patients with hepatitis C virus infection who received direct-acting antiviral therapy and achieved sustained virological response. 2018/05 Link
76. Original article　 Low incidence of hepatitis B virus reactivation and subsequent hepatitis in patients with chronic hepatitis C receiving direct-acting antiviral therapy. 2018/05 Link
77. Original article　 Sequential therapy involving an early switch from entecavir to pegylated interferon-α in Japanese patients with chronic hepatitis B. 2018/05 Link
78. Original article　 Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals. 2018/07 Link
79. Original article　 Amplification of bacterial genomic DNA from all ascitic fluids with a highly sensitive polymerase chain reaction. 2018/08 Link
80. Original article　 Extracellular Water to Total Body Water Ratio in Viral Liver Diseases: A Study Using Bioimpedance Analysis. 2018/08 Link
81. Original article　 The Relationship between Controlling Nutritional (CONUT) Score and Clinical Markers among Adults with Hepatitis C Virus Related Liver Cirrhosis. 2018/08 Link
82. Original article　 Circulating let-7 Levels in Serum Correlate With the Severity of Hepatic Fibrosis in Chronic Hepatitis C. 2018/10 Link
83. Original article　 Association of the Body Mass Index with the Presence of Gastroesophageal Varices in Compensated Cirrhotic Patients with Hepatitis C Viral Infection. 2018/11 Link
84. Original article　 Effect of Sarcopenia on Sleep Disturbance in Patients with Chronic Liver Diseases. 2018/12 Link
85. Original article　 Health-Related Quality of Life in Chronic Liver Diseases: A Strong Impact of Hand Grip Strength. 2018/12 Link
86. Original article　 Proposed model for the prediction of intrahepatic covalently closed circular DNA level in patients with chronic hepatitis B. 2019/03 Link
87. Original article　 Serum Zinc Concentration and Sarcopenia: A Close Linkage in Chronic Liver Diseases. 2019/03 Link
88. Original article　 Association between Sarcopenia and Depression in Patients with Chronic Liver Diseases. 2019/05 Link
89. Original article　 Combined Albumin-Bilirubin Grade and Skeletal Muscle Mass as a Predictor in Liver Cirrhosis. 2019/06 Link
90. Original article　 Comparison of liver stiffness assessment by transient elastography and shear wave elastography using six ultrasound devices. 2019/06 Link
91. Original article　 Association between Albumin-Bilirubin Grade and Non-Protein Respiratory Quotient in Patients with Chronic Liver Diseases. 2019/09 Link
92. Original article　 Significant Correlation Between Grip Strength and m2bpgi in Patients with Chronic Liver Diseases. 2019/09 Link
93. Original article　 Usefulness of Attenuation Imaging with an Ultrasound Scanner for the Evaluation of Hepatic Steatosis. 2019/10 Link
94. Original article　 Serum Zinc Level Classification System: Usefulness in Patients with Liver Cirrhosis 2019/11 Link
95. Original article　 Combined albumin-bilirubin grade and Mac-2 binding protein glycosylation isomer as a useful predictor in compensated liver cirrhosis. 2019/12 Link
96. Original article　 Impact of Sustained Virological Response for Gastroesophageal Varices in Hepatitis-C-Virus-Related Liver Cirrhosis. 2019/12 Link
97. Original article　 Proposal of predictive model on survival in unresectable pancreatic cancer receiving systemic chemotherapy. 2020/01 Link
98. Original article　 Serum zinc concentration and quality of life in chronic liver diseases. 2020/01 Link
99. Original article　 Serum Zinc Level and non-Protein Respiratory Quotient in Patients with Chronic Liver Diseases. 2020/01 Link
100. Original article　 Walking Speed: Japanese Data in Chronic Liver Diseases. 2020/01 Link
101. Original article　 Serum Zinc Level Grading System: A Useful Model for Composite Hepatic Events in Hepatitis C Virus-Associated Liver Cirrhosis. 2020/02 Link
102. Original article　 Japan Etiology of Liver Cirrhosis Study Group in the 54th Annual Meeting of JSH. Transition in the etiology of liver cirrhosis in Japan: a nationwide survey. 2020/03 Link
103. Original article　 The Anthropometric Assessment With the Bioimpedance Method Is Associated With the Prognosis of Cirrhotic Patients. 2020/04
104. Original article　 Serum Zinc Level Is Associated with Frailty in Chronic Liver Diseases 2020/05
105. Original article　 A New Ultrasonographic "Fluttering Sign" for Hepatic Hemangioma 2021/04
106. Original article　 Severity of liver fibrosis using shear wave elastography is influenced by hepatic necroinflammation in chronic hepatitis patients, but not in cirrhotic patients 2021/04
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■ Presentation
1. Malignant grading system including the evaluation of kupffer function for hepatocellular carcinoma using Sonazoid contrast enhanced ultrasonography.  2013/09/24
2. Analysis of risk factors for aiming at early detection of hepatocellular carcinoma.  2013/11/04
3. Spleen stiffness accurately predicts esophageal varices in patients with chronic liver disease regardless of the presence of portosystemic collaterals.  2013/11/04
4. Usefulness and challenges associated with the spleen stiffness via Virtual Quantification for the prediction of liver fibrosis.  2013/11/04
5. HDGF(hepatoma-derived growth factor)-silencing inhibits the proliferation of hepatoma cells through a sorafenib-independent pathway.  2013/11/05
6. The mitochondrial gene abnormalities and sustained pathological alterations in the liver after hepatitis C virus eradication  2013/11/05
7. Relationship between the mitochondria gene abnormality in liver tissues in patients with chronic viral hepatitis C and the hepatocarcinogenesis.  2014/11
8. Retrospective Cohort study for liver carcinogenesis prediction using VF map score : Virtual Touch Quantification(VTQ), Fasting blood glucose(FBG), male, age, platelet.  2014/11
9. Risk of esophageal varices predicted by share wave velocity.  2014/11
10. The pivotal role of anti-angiogenic activity in the in vivo antitumor effects of type I interferon.  2014/11
11. Feature of fibrosis diagnosis in hepatitis B patients.  2014/11/20
12. The presence of histological abnormalities even after the elimination of hepatitis C virus  2015/11/14
13. The relationship between the presence of esophageal varices and the Wisteria floribundaagglutinin-positive Mac-2-binding protein level in patients with Child-Pugh A liver cirrhosis.  2015/11/14
14. Pssible involovement of hepatic steatosis in the elevation of aminotransferases in hepatitis B virusinfected patients who are HBeAg-negative and have low DNA levels.  2015/11/16
15. Usefulness of spleen stiffness measurement using VTQ in diagnosing esophagogastric varices including the relationship with collateral vessels.  2015/11/16
16. Retrospective cohort study for liver carcinogenesis prediction among HBs antigen negative and anti-HCV antibody negative hepatitis patients.  2015/11/17
17. Pathogenesis of portal hypertension and the intrahepatic hemodynamics in liver cirrhosis.  2016/02
18. Concomitance of nonalcoholic fatty liver disease/steatohepatitis(NAFLD/NASH) is associated with the histological severity in Hepatitis B virus-infected liver.  2016/11/11
19. The diagnostic accuracy for liver fibrosis using shear wave elastography according to etiology of liver disease and the presence or absence of anti-viral therapy  2016/11/13
20. Comparison of FIB-4 index and aspartate aminotransferase to platelet ratio index on carcinogenesis in chronic hepatitis B treated with entecavir.  2016/11/14
21. Circulating let-7 levels in serum and extracel-lular vesicles correlate with hepatic fibrosis progression in chronic hepatitis.  2017/10/20 Link
22. The unique patterns of change in the metabolic variables of patients with primary biliary cholangitis.  2017/10/20 Link
23. The possible association between hepatic steatosis and decreased treatment efficacy in patients receiving sequential therapy for hepatitis B virus.  2017/10/21 Link
24. Efficacy and Safety of Sofosbuvir/Velpatasvir plus Ribavirin for 12 or 24 Weeks in Genotype 1 or 2 HCV-Infected Japanese Patients with Prior Treatment Failure to DAA-Based Regimens.  2017/10/23 Link
25. Low incidence of HBV reactivation and consequent hepatitis in patients with chronic hepatitis C receiving direct-acting antiviral therapy.  2017/10/23 Link
26. Shear wave elastography for the diagnosis of esophagogastric varices  2017/10/31
27. Study on the Influence of Fatty Liver Disease in Chronic Type B Liver Disease.  2018/11/12
28. Identification of microRNAs potentially associated with HDGF(hepatoma-derived growth factor)-stimulating cellular proliferation in hepatoma cells.  2019/10/01
29. Possible relevance of PNPLA3 gene polymorphism to hepatic steatosis and the efficacy of antiviral therapy for HBV infection.  2019/11/06
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