![]() Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Not refereed |
Title | Hypertrophic pachymeningitis in ANCA-associated vasculitis: a cross-sectional and multi-institutional study in Japan (J-CANVAS). |
Journal | Formal name:Arthritis research & therapy ISSN code:14786362/14786354/14786354 |
Domestic / Foregin | Foregin |
Volume, Number, Page | 24,pp.204 |
Papers・Author | Shimojima Yasuhiro, Kishida Dai, Ichikawa Takanori, Kida Takashi, Yajima Nobuyuki, Omura Satoshi, Nakagomi Daiki, Abe Yoshiyuki, Kadoya Masatoshi, Takizawa Naoho, Nomura Atsushi, Kukida Yuji, Kondo Naoya, Yamano Yasuhiko, Yanagida Takuya, Endo Koji, Hirata Shintaro, Matsui Kiyoshi, Takeuchi Tohru, Ichinose Kunihiro, Kato Masaru, Yanai Ryo, Matsuo Yusuke, Nishioka Ryo, Okazaki Ryota, Takata Tomoaki, Ito Takafumi, Moriyama Mayuko, Takatani Ayuko, Miyawaki Yoshia, Ito-Ihara Toshiko, Kawaguchi Takashi, Kawahito Yutaka, Sekijima Yoshiki. |
Publication date | 2022/08 |
Papers・Description | BACKGROUND: This study investigated the characteristics of hypertrophic pachymeningitis (HP) in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), using information from a multicenter study in Japan. METHODS: We analyzed the clinical information of 663 Asian patients with AAV (total AAV), including 558 patients with newly diagnosed AAV and 105 with relapsed AAV. Clinical findings were compared between patients with and without HP. To elucidate the relevant manifestations for HP development, multivariable logistic regression analyses were additionally performed. RESULTS: Of the patients with AAV (mean age, 70.2 ± 13.5 years), HP was noted in 30 (4.52%), including 20 (3.58%) with newly diagnosed AAV and 10 (9.52%) with relapsed AAV. Granulomatosis with polyangiitis (GPA) was classified in 50% of patients with HP. A higher prevalence of GPA was significantly observed in patients with HP than in those without HP in total AAV and newly diagnosed AAV (p < 0.001). |