教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | TAFRO syndrome with renal biopsy successfully treated with steroids and cyclosporine: a case report. |
掲載誌名 | 正式名:BMC nephrology ISSNコード:14712369 |
掲載区分 | 国外 |
巻・号・頁 | 23,pp.262 |
著者・共著者 | Iwasaki Takahide, Mizusaki Kosuke, Masumoto Miwa, Minagawa Yuko, Azuma Kouta, Furukawa Tetsuya, Yoshida Makoto, Kuragano Takahiro. |
発行年月 | 2022/07 |
概要 | BACKGROUND: TAFRO syndrome is an acute or subacute systemic inflammatory disease with no apparent cause, presenting with fever, generalized edema, thrombocytopenia, renal damage, anemia, and organ enlargement. Interleukin-6, vascular endothelial growth factor, and other cytokines are thought to be the etiologic agents that increase vascular permeability and cause the resulting organ damage. Only few reports of renal biopsy performed in patients with TAFRO syndrome exist. CASE PRESENTATION: A 61-year-old woman, with a history of Sjogren's syndrome, was admitted to our hospital with anasarca and abdominal distension. Based on the clinical course and various laboratory findings, we diagnosed TAFRO syndrome. Renal biopsy revealed thrombotic microangiopathy, including endothelial cell swelling, subendothelial space expansion, and mesangiolysis. |