教員業績データベース |
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論文種別 | 症例報告 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | Quantitative bone SPECT/CT for evaluating treatment response in patient with sternoclavicular arthritis. |
掲載誌名 | 正式名:Acta radiologica open ISSNコード:20584601 |
掲載区分 | 国外 |
巻・号・頁 | 11,pp.20584601221128409 |
著者・共著者 | Komoto Hisashi, Kitajima Kazuhiro, Azuma Naoto, Tamura Masao, Yokoyama Hiroyuki, Tsuchitani Tatsuya, Yamakado Koichiro. |
発行年月 | 2022/10 |
概要 | We report here a case of sternoclavicular arthritis due to SAPHO syndrome in a 60-year-old female in which quantitative values determined using bone SPECT/CT were useful to evaluate response. After celecoxib and alendronate sodium hydrate therapy, the chief complaints were well relieved and post-treatment Tc-99m HMDP bone SPECT/CT examination showed decreased uptake. The maximum standardized uptake value (SUV), peak SUV, mean SUV, metabolic bone volume, and total bone uptake of the untreated lesion were 18, 16, 10, 17 mL, and 180, respectively, which were decreased to 8, 7, 5, 15 mL, and 75, respectively, after the treatment. In comparison with pre-treatment situation, those parameters were decreased by -56%, -56%, -50%, -12%, and -58%, respectively, following celecoxib and alendronate sodium hydrate therapy, likely reflecting treatment response. Quantitative bone SPECT/CT may be useful to evaluate joint inflammatory activity and treatment response in a patient with osteoartritis. |