教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Effect of Muscle Loss but Not Fat Loss during Primary Debulking Surgery and Chemotherapy on Prognosis of Patients with Ovarian Cancer. |
掲載誌名 | 正式名:Journal of clinical medicine 略 称:J Clin Med ISSNコード:20770383/20770383 |
掲載区分 | 国外 |
巻・号・頁 | 11(11),pp.11 |
著者・共著者 | Nakayama Naomi, Nakayama Kentaro, Ishibashi Tomoka, Katayama Satoru, Kyo Satoru |
発行年月 | 2022/06 |
概要 | Although the negative effect of muscle loss during invasive treatment has been widely reported in patients with cancer, its value in patients with ovarian cancer is not clear. Therefore, this study was conducted to clarify whether muscle loss during cytoreductive surgery and chemotherapy affects prognosis in patients with ovarian cancer. We retrospectively recruited 58 patients with ovarian cancer who underwent site reductive surgery and chemotherapy at Shimane University Hospital from March 2006 to November 2013 and for whom pre- and postoperative computed tomography were available. Skeletal muscle changes and fat mass volume during primary debulking surgery and chemotherapy were subsequently investigated at the level of the third lumbar vertebra. Muscle and fat mass loss occurred independently in half of the patients. Muscle loss, but not fat loss, was associated with disease-free survival (p = 0.041 and p = 0.794, respectively) and poor overall survival (p = |
DOI | 10.3390/jcm11113184 |
PMID | 35683568 |