教員業績データベース |
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論文種別 | 総説 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Effect of Routine Varicella Immunization on the Epidemiology and Immunogenicity of Varicella and Shingles. |
掲載誌名 | 正式名:Viruses ISSNコード:19994915 |
掲載区分 | 国外 |
巻・号・頁 | 14,pp.1-7 |
著者・共著者 | Otani N, Shima M, Yamamoto T, Okuno T |
発行年月 | 2022/03 |
概要 | Varicella-zoster virus (VZV) causes varicella as a primary infection and remains latent in the ganglia until it becomes reactivated to cause herpes zoster. Individuals with varicella develop adaptive humoral and cell-mediated immunity. Compromised cell-mediated immunity is thought to contribute to the development of herpes zoster. Recent evidence suggests that changes in the epidemiology of varicella have affected the epidemiology of herpes zoster. The incidence of herpes zoster is higher in older adults; thus, the herpes zoster vaccine is recommended for older adults. However, the incidence of herpes zoster is expected to rise among younger individuals; hence, vaccination with the varicella vaccine should also be considered in younger adults. In order to determine the need for vaccination in different populations, it is important to establish methods to accurately assess the activity of cell-mediated immunity and humoral immunity. |