Faculty Information |
|
Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in mice. |
Journal | Formal name:Biochemistry and biophysics reports Abbreviation:Biochem Biophys Rep ISSN code:2405580824055808 |
Domestic / Foregin | Foregin |
Volume, Number, Page | 21,pp.100738 |
Papers・Author | Shindo Ryodai, Katagiri Takaharu, Komazawa-Sakon Sachiko, Ohmuraya Masaki, Takeda Wakami, Nakagawa Yoshiko, Nakagata Naomi, Sakuma Tetsushi, Yamamoto Takashi, Nishiyama Chiharu, Nishina Takashi, Yamazaki Soh, Kameda Hideto, Nakano Hiroyasu |
Publication date | 2020/03 |
Papers・Description | Regenerating islet-derived protein (Reg)3β belongs to a member of the Reg family of proteins and has pleiotropic functions, including antimicrobial activity and tissue repair. However, whether Reg3β plays a protective role in the development of colitis and ileitis has not been fully investigated. We generated transgenic mice expressing a short form of cellular FLICE-inhibitory protein (cFLIPs) that promotes necroptosis, a regulated form of cell death. cFLIPs transgenic (CFLARs |
DOI | 10.1016/j.bbrep.2020.100738 |
PMID | 32072024 |