Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Comparison of angioscopy and histopathology for the evaluation of carotid plaque characteristics: an ex vivo validation study. |
Journal | Formal name:The international journal of cardiovascular imaging Abbreviation:Int J Cardiovasc Imaging ISSN code:1875831215695794 |
Domestic / Foregin | Foregin |
Volume, Number, Page | 36(2),pp.231-9 |
Papers・Author | Kawai Kenji, Fujii Kenichi, Shirakawa Manabu, Uchida Kazutaka, Yamada Kiyofumi, Kawakami Rika, Imanaka Takahiro, Hao Hiroyuki, Hirota Seiichi, Ishihara Masaharu, Yoshimura Shinichi |
Publication date | 2020/02 |
Papers・Description | Intravascular angioscopy is widely used for evaluating plaque characteristics through the plaque color in the coronary artery. This study evaluated whether angioscopy is capable of identifying various plaque morphologies, including necrotic core and intraplaque hemorrhage (IPH) in the carotid artery. Nine patients underwent carotid endarterectomy for carotid artery stenosis, and these specimens were imaged ex vivo by angioscopy within 6 h. An angioscopic examination of carotid plaque evaluated its color intensity as follows: white, yellow, or red. The IPH area, necrotic core area, and fibrous cap thickness was measured on histological sections at each site. A total of 7 plaques were graded as white plaques, 10 as yellow, and 8 as red by angioscopy. The IPH area and the percent area occupied by IPH were larger in red and yellow plaques than in white plaques (10.7 ± 9.3 mm2 |
DOI | 10.1007/s10554-019-01720-8 |
PMID | 31664681 |