教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Breathing-swallowing discoordination is associated with frequent exacerbations of COPD. |
掲載誌名 | 正式名:BMJ open respiratory research 略 称:BMJ Open Respir Res ISSNコード:2052443920524439 |
掲載区分 | 国外 |
巻・号・頁 | 4(1),pp.e000202 |
著者・共著者 | Nagami Shinsuke, Oku Yoshitaka, Yagi Naomi, Sato Susumu, Uozumi Ryuji, Morita Satoshi, Yamagata Yoshie, Kayashita Jun, Tanimura Kazuya, Sato Atsuyasu, Takahashi Ryosuke, Muro Shigeo |
発行年月 | 2017 |
概要 | INTRODUCTION:Impaired coordination between breathing and swallowing (breathing-swallowing discoordination) may be a significant risk factor for the exacerbation of chronicobstructive pulmonary disease (COPD). We examined breathing-swallowing discoordination in patients with COPD using a non-invasive and quantitative technique and determined its association with COPD exacerbation.METHODS:We recruited 65 stable outpatients with COPD who were enrolled in our prospective observational cohort study and did not manifest an apparent swallowing disorder. COPD exacerbation was monitored for 1 year before and 1 year after recruitment. Swallowing during inspiration (the I-SW pattern) and swallowing immediately followed by inspiration (the SW-I pattern) were identified.RESULTS:The mean frequency of the I-SW and/or SW-I patterns (I-SW/SW-I rate) was 21.5%±25.5%. During the 2-year observation period, 48 exacerbation incidents (25 patients) were identified. |
DOI | 10.1136/bmjresp-2017-000202 |
PMID | 28883930 |