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Article types Case report
Language English
Refereed paper Refereed
Title Pazopanib treatment of a platinum-resistant recurrence of a high-grade Sertoli cell tumor and assessment of the treatment response by FDG-PET/CT: A case report.
Journal Formal name:Gynecologic oncology reports
Abbreviation:Gynecol Oncol Rep
ISSN code:2352-5789(Print)2352-5789(Linking)
Domestic / ForeginForegin
Volume, Number, Page 24,pp.54-56
Papers・Author Inoue Kayo, Tsubamoto Hiroshi, Ishida-Nisigami Keiko, Torii Yoshitaka, Hirota Seiichi
Publication date 2018/05
Papers・Description Ovarian Sertoli cell tumors (SCTs) are rare sex cord tumors (Oliva et al., 2005). The standard treatment for high-grade SCTs is surgery followed by platinum-based chemotherapy. Although platinum-based chemotherapy is also an option for recurrent SCTs (Sigismondiet al., 2012), there is no established chemotherapy regimen for platinum-resistant recurrent SCTs. The effectiveness of pazopanib in treating epithelial ovarian cancer has recently been reported (du Bois et al., 2014; Pignata et al., 2015). In the case described herein, pazopanib was used to treat the platinum-resistant recurrence of a high-grade Sertoli cell tumor, and the response was evaluated by 18F-fluoro-deoxyglucose positron emission tomography (FDG-PET)-computed tomography (CT). Written informed consent to reporting the case was obtained from the patient.
DOI 10.1016/j.gore.2018.03.002
PMID 29915800