Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction: J-MINUET substudy. |
Journal | Formal name:Journal of cardiology Abbreviation:J Cardiol ISSN code:1876-4738(Electronic)0914-5087(Linking) |
Domestic / Foregin | Domestic |
Volume, Number, Page | 70(6),pp.553-8 |
Papers・Author | Ogita Manabu, Suwa Satoru, Ebina Hideki, Nakao Koichi, Ozaki Yukio, Kimura Kazuo, Ako Junya, Noguchi Teruo, Yasuda Satoshi, Fujimoto Kazuteru, Nakama Yasuharu, Morita Takashi, Shimizu Wataru, Saito Yoshihiko, Hirohata Atsushi, Morita Yasuhiro, Inoue Teruo, Okamura Atsunori, Uematsu Masaaki, Hirata Kazuhito, Tanabe Kengo, Shibata Yoshisato, Owa Mafumi, Hokimoto Seiji, Funayama Hiroshi, Kokubu Nobuaki, Kozuma Ken, Uemura Shiro, Toubaru Tetsuya, Saku Keijiro, Oshima Shigeru, Nishimura Kunihiro, Miyamoto Yoshihiro, Ishihara Masaharu |
Publication date | 2017/12 |
Papers・Description | BACKGROUND:The association between patients with acute myocardial infarction (AMI) who present during off-hours and clinical outcomes has not been fully elucidated.METHODS:We investigated 3283 consecutive patients with AMI who were selected from a prospective, nationwide, multicenter registry (J-MINUET) database comprising 28 institutions in Japan between July 2012 and March 2014 to determine the current impact of off-hours presentation on in-hospitalmortality among Japanese patients with AMI.RESULTS:Among the patients, 52% presented in off-hours. Baseline characteristics were comparable, although those who presented during off-hours were younger and had a higher incidence of ST-elevation myocardial infarction and advanced Killip Class. The time from symptom onset to presentation time was shorter in off-hour patients (120min, interquartile range 60 to 256 vs. 215min, interquartile range 90 to 610, p<0.0001). In contrast, 85% of patients underwent primary percutaneous coronary intervention (PCI) and door to balloon time was comparable between the groups (74min, interquartile range 52 to 113 vs. 75min, interquartile range 52 to 126, p=0.34). The rates of in-hospital mortality were comparable (6.2% vs 6.8%, p=0.39). Multivariate logistic regression analysis revealed that off-hours presentation was not significantly associated with in-hospital mortality [odds ratio (OR) 0.94; 95% CI, 0.68-1.30, p=0.70].CONCLUSION:The clinical impact of presenting during off-hours or regular hours on AMI patients in Japan is comparable in contemporary practice.TRIAL REGISTRATION:UMIN Unique trial Number: UMIN000010037. |
DOI | 10.1016/j.jjcc.2017.05.006 |
PMID | 28684209 |