教員業績データベース |
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論文種別 | 原著 |
言語種別 | 日本語 |
査読の有無 | 査読なし |
表題 | Role of surgery in delayed local treatment for INSS 4 neuroblastoma |
掲載誌名 | 正式名:Pediatrics international : official journal of the Japan Pediatric Society 略 称:Pediatr Int ISSNコード:1442-200X(Electronic)1328-8067(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 59(9),986-90頁 |
著者・共著者 | Uehara Shuichiro, Yoneda Akihiro, Oue Takaharu, Nakahata Kengo, Zenitani Masahiro, Miyamura Takako, Hashii Yoshiko, Fukuzawa Masahiro, Okuyama Hiroomi |
発行年月 | 2017/09 |
概要 | BACKGROUND:The aim of the present study was to compare the efficacy, complications and outcomes of the following two surgical strategies for delayed local treatment for International Neuroblastoma Staging System (INSS) 4 neuroblastoma (NB): complete resection (CR; period A); and gross total resection/subtotal resection (GTR/STR) with local irradiation (period B).METHODS:We retrospectively analyzed 17 patients with INSS 4 NB who received delayed local treatment (period A, n = 11; period B, n = 6).RESULTS:Eleven patients in period A received CR. Two patients underwent GTR and four patients underwent STR in period B. The amount of blood loss in period A was significantly greater than that in period B. Postoperative complications were observedin eight patients in period A (73%), but in only one patient in period B (17%; P < 0.01). Recurrence was observed in five patients in period A and in one patient in period B (45.4% vs 16.6%; P = n.s.). Distant metastasis at recurrence was observed in four patients in period A and in one patient in period B.CONCLUSIONS:Gross total resection/subtotal resection with local irradiation may be a safe and effective delayed local treatment for INSS 4 NB. |
DOI | 10.1111/ped.13349 |
PMID | 28643949 |