教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | The distribution of calcified nodule and plaque rupture in patients with peripheral artery disease: an intravascular ultrasound analysis. |
掲載誌名 | 正式名:Heart and vessels 略 称:Heart Vessels ISSNコード:1615-2573(Electronic)0910-8327(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 32(10),pp.1161-8 |
著者・共著者 | Horimatsu Tetsuo, Fujii Kenichi, Fukunaga Masashi, Miki Kojiro, Nishimura Machiko, Naito Yoshiro, Shibuya Masahiko, Imanaka Takahiro, Kawai Kenji, Tamaru Hiroto, Sumiyoshi Akinori, Saita Ten, Masuyama Tohru, Ishihara Masaharu |
発行年月 | 2017/05 |
概要 | In addition to plaque rupture (PR), calcified nodule (CN) may also have the potential to develop into arterial thrombus in the peripheral arteries. This study evaluated the distribution of plaque ruptures and calcified nodules in the peripheral arteries and their impact on the outcome of endovascular therapy (EVT). Consecutive 159 patients who underwent EVT with intravascular ultrasound guidance were enrolled. The position of CNs and PRs were assigned to any of common iliac artery, external iliac artery, common femoral artery, and superficial femoral artery. Forty-six (29%) patients had calcified nodule and twenty-eight (18%) patients had plaque rupture somewhere in the lower limb arteries. Although calcified nodules were evenly distributed throughout the length of the arteries plaque ruptures were predominantly located in the proximal segment of the iliofemoral arteries. Stent expansion ratio was significantly smaller in the target arteries with calcified nodules than in those with plaque rupture. Multivariate logistic regression analysis identified hemodialysis as an independent clinical predictor of calcified nodule (odds ratio 8.15, 95% confidenceinterval 1.73-38.3; P = 0.008). CN definitely affects incomplete stent deployment in the peripheral artery contributing to adverse events, on the other hand, PR has more acceptable outcomes after stent implantation. In the clinical setting, it is important that we realize the features of peripheral artery disease and its patient characteristics which having CNs and PRs to make a strategy for revascularization. |
DOI | 10.1007/s00380-017-0984-5 |
PMID | 28466410 |