Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Impact of thermodilution-derived coronary blood flow patterns after percutaneous coronary intervention on mid-term left ventricular remodeling in patients with ST elevation myocardial infarction. |
Journal | Formal name:Heart and vessels Abbreviation:Heart Vessels ISSN code:1615-2573(Electronic)0910-8327(Linking) |
Domestic / Foregin | Foregin |
Volume, Number, Page | 32(1),pp.1-7 |
Papers・Author | Sumiyoshi Akinori, Fujii Kenichi, Fukunaga Masashi, Shibuya Masahiko, Imanaka Takahiro, Kawai Kenji, Miki Kojiro, Tamaru Hiroto, Horimatsu Tetsuo, Saita Ten, Nishimura Machiko, Masuyama Tohru, Ishihara Masaharu |
Publication date | 2017/01 |
Papers・Description | UNASSIGNED:We recently reported the coronary thermodilution curve can be evaluated by analyzing the thermodilution curve obtained from a pressure sensor/thermistor-tipped guidewire, and presence of a bimodal-shaped thermodilution curve following primary percutaneous coronary intervention (pPCI) in ST-segment elevation myocardial infarction (STEMI) patients was associated with worse outcomes. This study evaluated whether the bimodal-shaped thermodilution curve predicts left ventricular (LV) remodeling after STEMI. The coronary thermodilution curve patterns were evaluated for 75 patients treated by pPCI for their first STEMI using a pressure sensor/thermistor-tipped guidewire, and classified into the three groups according to the thermodilution curve shape: narrow unimodal (n = 39), wide unimodal (n = 26), and bimodal pattern (n = 10). Echocardiography was performed at baseline and 6 months after STEMI. LV remodeling was defined as a >20 % increase in LV end-diastolic volumes (LVEDV). LVEDV at 6-month follow-up was greater in the bimodal group than in the other groups (p < 0.001). The prevalence of LV remodeling was highest in the bimodal group than in the narrow and wide unimodal groups (60, 12, and 15 %, respectively; p = 0.003). Multivariate analysis revealed a bimodal-shaped thermodilution curve as an independent predictor of the prevalence of LV remodeling. A bimodal-shaped thermodilution curve is associated with LV remodeling after STEMI. This easily assessable coronary thermodilution curve pattern is useful to predict mid-term LV remodeling for STEMI patients at the catheterization laboratory. |
DOI | 10.1007/s00380-016-0831-0 |
PMID | 27048558 |