教員業績データベース |
|
論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | The impact of left atrial pressure on filtered P-wave duration in patients with atrial fibrillation. |
掲載誌名 | 正式名:Heart and vessels 略 称:Heart Vessels ISSNコード:1615-2573(Electronic)0910-8327(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 31(11),pp.1848-54 |
著者・共著者 | Kishima Hideyuki, Mine Takanao, Takahashi Satoshi, Ashida Kenki, Ishihara Masaharu, Masuyama Tohru |
発行年月 | 2016/11 |
概要 | UNASSIGNED:The cause of prolonged filtered P-wave duration (FPD) remains unclear in atrial fibrillation (AF) patients with normal left atrial size. We investigated whether FPD is associated with left atrial pressure (LAP) in AF patients without prominent LA enlargement. This study included 80 patients (48 men, age 65 ± 9 years, 25 persistent AF) with non-valvular AF who underwent catheter ablation (CA) for AF. LAP was measured in sinus rhythm during CA and signal-averaged electrocardiogram was recorded after CA. We retrospectively assessed the clinical and echocardiographic variables. Prolonged FPD was defined aUNASSIGNED:s FPD UNASSIGNED:>UNASSIGNED: 120 ms. Prolonged FPD (FPD UNASSIGNED:>UNASSIGNED: 120 ms) was detected in 23/80 patients (29 %). According to univariate analysis, higher mean LAP (14.9 ± 4.4 vs. 10.8 ± 3.5 mmHg, p UNASSIGNED:<UNASSIGNED: 0.0001), higher prevalence of persistent arrhythmia, higher BNP, larger LAD, higher E wave, and lower LVEF were associated with Prolonged FPD. According to multivariate analysis, higher mean LAP was the only factor associated with Prolonged FPD (p = 0.0058, OR 1.256 for each 1 mmHg increase in mean LAP, 95 % CI 1.068-1.476). Moreover, a significant correlation was observed between FPD and mean LAP (r = 0.503, p UNASSIGNED:<UNASSIGNED: 0.0001). Prolonged FPD is associated with high LAP in AF patients without prominent left atrial enlargement. Pressure overload of the left atria might cause slowing of atrial electrical activation. |
DOI | 10.1007/s00380-015-0789-3 |
PMID | 26733459 |