Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Not refereed |
Title | Residual total pancreatectomy: Short- and long-term outcomes. |
Journal | Formal name:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Abbreviation:Pancreatology ISSN code:1424-3911(Electronic)1424-3903(Linking) |
Volume, Number, Page | 16(4),pp.646-51 |
Papers・Author | Hashimoto Daisuke, Chikamoto Akira, Taki Katsunobu, Arima Kota, Yamashita Yo-Ichi, Ohmuraya Masaki, Hirota Masahiko, Baba Hideo |
Publication date | 2016/08 |
Papers・Description | BACKGROUND/OBJECTIVES:Because of limited numbers of patients, there are limited data available regarding outcomes after residual total pancreatectomy (R-TP). This study aimed to assess outcomes after the R-TP vs the one-stage total pancreatectomy (O-TP), especially focused on the pancreatic adenocarcinoma cases.METHODS:From 2005 to 2014, all patients who underwent the R-TP (n = 8) and the O-TP (n = 12) for pancreatic primary malignancy were prospectively enrolled.RESULTS:The median time from the initial operation to the R-TP was 30 months. Ten patients in the O-TP group and 8 in the R-TP had pancreatic adenocarcinoma. Postoperative complications occurred in two O-TP patients and one R-TP patient. There was no in-hospital mortality. At 12 months after surgery, the median insulin dose was 27 U/day after the O-TP and 24 U/day after the R-TP, the median hemoglobin A1c was 7.2% after the O-TP and 6.9% after the R-TP. There was a significantly larger reduction in body weight after the O-TP than after the R-TP. Postoperative fatty liver disease occurred in about half of the patients in each group. In patients with pancreatic adenocarcinoma, the 2-year overall survival rate was not significantly different (68.6% after the O-TP vs 71.4% after the R-TP).CONCLUSIONS:Although the postoperative morbidity and nutritional statuses should be improved, these favorable short- and long-term outcomes demonstrate that the R-TP is a feasible procedure for patients with malignant tumor in the remnant pancreas. |
DOI | 10.1016/j.pan.2016.04.034 |
PMID | 27189919 |