教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | Extension of recovery time from fatigue by repeated rest with short-term sleep during continuous fatigue load: Development of chronic fatigue model |
掲載誌名 | 正式名:Journal of neuroscience research 略 称:J Neurosci Res ISSNコード:03604012/10974547 |
掲載区分 | 国外 |
出版社 | Wiley Periodicals, Inc. |
巻・号・頁 | 94(5),pp.424-9 |
著者・共著者 | Kanzaki A, Okauchi T, Hu D, Shingaki T, Katayama Y, Koyama Hidenori, Watanabe Y, Cui Y. |
発行年月 | 2016/05 |
概要 | Homeostasis is known to be involved in maintaining the optimal internal environment, helping to achieve the best performance of biological functions. At the same time, a deviation from optimal conditions often attenuates the performance of biological functions, and such restricted performance could be considered as individual fatigue, including physical and mental fatigue. The present study seeks to develop an animal model of chronic or subacute fatigue in which the recovery time is extended through the gradual disruption of homeostasis. We show that repeated short-term rest periods with certain lengths of sleep during continuous fatigue loading extend recovery from spontaneous nighttime activity but not physical performance in comparison with a continuous fatigue-loading procedure. Furthermore, the immobility time in a forced swimming test was extended by repeated short-term rests. These results suggest that repeated short-term rest with certain lengths of sleep during continuous fatigue loading is able to extend the recovery from mental fatigue but not from physical fatigue and that this effect might occur via the disruption of a homeostatic mechanism that is involved in restoring the optimal internal environment. |
DOI | 10.1002/jnr.23718 |
PMID | 26864568 |