Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Angioscopic comparison of arterial repair after second-generation drug-eluting stent implantation into vulnerable and stable coronary plaques. |
Journal | Formal name:International journal of cardiology Abbreviation:Int J Cardiol ISSN code:1874-1754(Electronic)0167-5273(Linking) |
Domestic / Foregin | Foregin |
Volume, Number, Page | 221,pp.855-8 |
Papers・Author | Kawai Kenji, Ichikawa Minoru, Masuyama Tohru, Kijima Yoshiyuki |
Publication date | 2016/10 |
Papers・Description | BACKGROUND:Arterial repair after intracoronary stenting depends on stent types and plaque vulnerability. The aim of this study was angioscopic comparison of arterial repair after implantation of the second-generation drug-eluting stents (G2-DES) between the stable and vulnerable plaques.METHODS:Four types of G2-DES were successfully implanted into stable plaques (n=41) and vulnerable plaques (n=34): 13 and 9 XiMETHODS:ence-everolimus-, 7 and 6 Endeavor-zotarolimus-, 15 and 9 Resolute-zotarolimus-, and 6 and 10 Nobori-biolimus-eluting stents (EES, E-ZES, R-ZES, and BES), respectively. Coronary angioscopy at 1-year follow-up revealed in-stent appearance, such as neointimal stent coverage (NSC), presence of yellow plaques (YP), and in-stent mural thrombus (MT). NSC was graded into poor and good coverage.RESULTS:Yellow plaques and mural thrombi were found more frequently in the vulnerable plaques than in the stable plaques (29% vs. 12%, P=0.06; 12 vs. 0%, P=0.02; respectively). In EES, poor NSC was observed more frequently in the vulnerable plaques than in the stable plaques (54% vs. 11%, P=0.04). In BES, YP was observed more frequently in the vulnerable plaques than in the stable plaques (80% vs. 17%, P=0.01). In E-ZES and R-ZES, there were no significant differences with regards to angioscopic parameters between the stable and vulnerable plaques.CONCLUSIONS:Arterial repair after EES and BES implantation into the vulnerable plaques remained vulnerable even at 1-year follow-up. |
DOI | 10.1016/j.ijcard.2016.07.089 |
PMID | 27434360 |