教員業績データベース |
|
論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Angioscopic comparison of arterial repair after second-generation drug-eluting stent implantation into vulnerable and stable coronary plaques. |
掲載誌名 | 正式名:International journal of cardiology 略 称:Int J Cardiol ISSNコード:1874-1754(Electronic)0167-5273(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 221,pp.855-8 |
著者・共著者 | Kawai Kenji, Ichikawa Minoru, Masuyama Tohru, Kijima Yoshiyuki |
発行年月 | 2016/10 |
概要 | BACKGROUND:Arterial repair after intracoronary stenting depends on stent types and plaque vulnerability. The aim of this study was angioscopic comparison of arterial repair after implantation of the second-generation drug-eluting stents (G2-DES) between the stable and vulnerable plaques.METHODS:Four types of G2-DES were successfully implanted into stable plaques (n=41) and vulnerable plaques (n=34): 13 and 9 XiMETHODS:ence-everolimus-, 7 and 6 Endeavor-zotarolimus-, 15 and 9 Resolute-zotarolimus-, and 6 and 10 Nobori-biolimus-eluting stents (EES, E-ZES, R-ZES, and BES), respectively. Coronary angioscopy at 1-year follow-up revealed in-stent appearance, such as neointimal stent coverage (NSC), presence of yellow plaques (YP), and in-stent mural thrombus (MT). NSC was graded into poor and good coverage.RESULTS:Yellow plaques and mural thrombi were found more frequently in the vulnerable plaques than in the stable plaques (29% vs. 12%, P=0.06; 12 vs. 0%, P=0.02; respectively). In EES, poor NSC was observed more frequently in the vulnerable plaques than in the stable plaques (54% vs. 11%, P=0.04). In BES, YP was observed more frequently in the vulnerable plaques than in the stable plaques (80% vs. 17%, P=0.01). In E-ZES and R-ZES, there were no significant differences with regards to angioscopic parameters between the stable and vulnerable plaques.CONCLUSIONS:Arterial repair after EES and BES implantation into the vulnerable plaques remained vulnerable even at 1-year follow-up. |
DOI | 10.1016/j.ijcard.2016.07.089 |
PMID | 27434360 |