Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Morphologic remodeling of left atrial appendage in patients with atrial fibrillation. |
Journal | Formal name:Heart rhythm : the official journal of the Heart Rhythm Society Abbreviation:Heart Rhythm ISSN code:1556-3871(Electronic)1547-5271(Linking) |
Domestic / Foregin | Foregin |
Volume, Number, Page | 13(9),pp.1823-8 |
Papers・Author | Kishima Hideyuki, Mine Takanao, Takahashi Satoshi, Ashida Kenki, Ishihara Masaharu, Masuyama Tohru |
Publication date | 2016/09 |
Papers・Description | BACKGROUND:Left atrial appendage (LAA) has recently been of significant focus because of the development of the LAA closure device.OBJECTIVE:The purpose of this study was to test the hypothesis that atrial fibrillation (AF) leads to a morphologic change in the LAA and to investigate the characteristics of LAA morphology in patients with and without AF.METHODS:This retMETHODS:rospective study included 225 patients (persistent AF [PeAFMETHODS:]METHODS:, n = 76; paroxysmal AF [PAFMETHODS:]METHODS:, n = 70; control, n = 79METHODS:]METHODS:who underwent echocardiography and computed tomography (CT). All patients were classified into 2 types (chicken wing [CWMETHODS:]METHODS:or non-chicken wing [non-CWMETHODS:]METHODS:) using CT.RESULTS:The prevalence of non-CW-type LAA was 39.5%, 15.7%, and 8.9% in the PeAF, PAF, and control groups, respectively. Patients in the PeAF group had a higher prevalence of non-CW-type LAA than did those in the PAF and control groups (P = .0014 and PRESULTS:<RESULTS:.0001, respectively). In addition, all patients were divided into 5 groups based on the type of cardiac rhythm (PeAF, PAF, or sinus rhythm) and left atrial volume index (cutoff value; 34 mL/m(2)): group A (Control), group B (PAF/Small-LA), group C (PAF/Large-LA), group D (PeAF/Small-LA), group E (PeAF/Large-LA). The prevalence of non-CW-type LAA was 9%, 14%, 17%, 29%, and 41% in groups A, B, C, D, and E, respectively.CONCLUSION:Presence of persistent AF was associated with a higher prevalence of non-chicken wing-type LAA. Our analysis suggests that remodeling in patients with persistent AF can lead to a change in LAA morphology. |
DOI | 10.1016/j.hrthm.2016.06.009 |
PMID | 27291510 |