教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | The Impact of Elevated Left Atrial Pressure in Sinus Rhythm After Cardioversion on Outcomes After Catheter Ablation for Atrial Fibrillation. |
掲載誌名 | 正式名:Journal of cardiovascular electrophysiology 略 称:J Cardiovasc Electrophysiol ISSNコード:1540-8167(Electronic)1045-3873(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 27(7),pp.813-9 |
著者・共著者 | Kishima Hideyuki, Mine Takanao, Takahashi Satoshi, Ashida Kenki, Ishihara Masaharu, Masuyama Tohru |
発行年月 | 2016/07 |
概要 | INTRODUCTION:Some patients with atrial fibrillation (AF) exhibit elevated left atrial pressure (LAP) in sinus rhythm (SR). The aim of the study was to investigate whether LAP changes between SR and AF are associated with outcomes after catheter ablation (CA) for AF.METHODS AND RESULTS:We retrospectively studied 110 patients (70 men, 66 ± 8 years, 37 with non-paroxysmal AF) who underwent CA of AF. In all patients, AF was induced by programmed stimulation and then terminated with cardioversioMETHODS AND RESULTS:n during CA. LAP was measured in SR and AF. The LAPSR-AF was defined as the difference between mean LAP in SR and mean LAP in AF (mean LAPSR - mean LAPAF ). Recurrence of AF after CA was detected in 37/110 patients (33.6%) during the follow-up period (13 ± 5 months). Univariate analysis revealed higher LAPSR-AF , larger left atrial diameter, and persistent AF (PeAF) as significant variables. On multivariate analysis, higher LAPSR-AF and PeAF were independently associated with recurrence of AF after CA. All patients were divided into the non-elevated LAPSR-AF group (LAPSR-AFMETHODS AND RESULTS:<METHODS AND RESULTS:0 mmHg) or the elevated LAPSR-AF group (LAPSR-AF ≥0 mmHg) using the optimal cut-off value of LAPSR-AF . During a mean follow-up period of 13 ± 5 months, the AF recurrence ratio was higher in the elevated LAPSR-AF group than in the non-elevated LAPSR-AF group (20/42 patients, 48% vs. 17/68 patients, 25%, log-rank, P = 0.0306).CONCLUSION:Elevated LAP after cardioversion is associated with poor outcome after CA of AF. Sustained pressure overload of the LA in SR could be a cause of the recurrent AF. |
DOI | 10.1111/jce.12993 |
PMID | 27090869 |