Faculty Information |
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Article types | Introduction |
Language | English |
Refereed paper | Refereed |
Title | Nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan. |
Journal | Formal name:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Abbreviation:J Infect Chemother ISSN code:1437-7780(Electronic)1341-321X(Linking) |
Domestic / Foregin | Foregin |
Volume, Number, Page | 22(9),pp.581-6 |
Papers・Author | Takahashi Satoshi, Hamasuna Ryoichi, Yasuda Mitsuru, Ishikawa Kiyohito, Hayami Hiroshi, Uehara Shinya, Yamamoto Shingo, Minamitani Shinichi, Kadota Junichi, Iwata Satoshi, Kaku Mitsuo, Watanabe Akira, Sato Junko, Hanaki Hideaki, Masumori Naoya, Kiyota Hiroshi, Egawa Shin, Tanaka Kazushi, Arakawa Soichi, Fujisawa Masato, Kumon Hiromi, Wada Koichiro, Kobayashi Kanao, Matsubara Akio, Matsumoto Tetsuro, Eto Masatoshi, Tatsugami Katsunori, Kuroiwa Kentaro, Ito Kenji, Hosobe Takahide, Hirayama Hideo, Narita Harunori, Yamaguchi Takamasa, Ito Shin, Sumii Toru, Kawai Shuichi, Kanokogi Mototsugu, Kawano Hiromi, Chokyu Hirofumi, Uno Satoshi, Monden Koichi, Kaji Shinichi, Kawahara Motoshi, Takayama Kazuo, Ito Masayasu, Yoshioka Masaru, Kano Motonori, Konishi Takatoshi, Kadena Hitoshi, Nishi Shohei, Nishimura Hirofumi, Yamauchi Takamine, Maeda Shinichi, Horie Masanobu, Ihara Hideari, Matsumura Masaru, Shirane Takeshi, Takeyama Koh, Akiyama Kikuo, Takahashi Koichi, Ikuyama Toshihiro, Inatomi Hisato |
Publication date | 2016/09 |
Papers・Description | Genital chlamydial infection is a principal sexually transmitted infection worldwide. Chlamydia trachomatis can cause male urethritis, acute epididymitis, cervicitis, and pelvic inflammatory disease as sexually transmitted infections. Fortunately, homotypic resistant C. trachomatis strains have not been isolated to date; however, several studies have reported the isolation of heterotypic resistant strains from patients. In this surveillance study, clinical urethral discharge specimens were collected from patients with urethritis in 51 hospitals and clinics in 2009 and 38 in 2012. Based on serial cultures, the minimum inhibitory concentration (MIC) could be determined for 19 isolates in 2009 and 39 in 2012. In 2009 and 2012, the MICs (MIC90) of ciprofloxacin, levofloxacin, tosufloxacin, sitafloxacin, doxycycline, minocycline, erythromycin, clarithromycin, and azithromycin were 2 μg/ml and 1 μg/ml, 0.5 μg/ml and 0.5 μg/ml, 0.125 μg/ml and 0.125 μg/ml, 0.063 μg/ml and 0.063 μg/ml, 0.125 μg/ml and 0.125 μg/ml, 0.125 μg/ml and 0.125 μg/ml, 0.016 μg/ml and 0.016 μg/ml, and 0.063 μg/ml and 0.063 μg/ml, respectively. In summary, this surveillance project did not identify any resistant strain against fluoroquinolone, tetracycline, or macrolide agents in Japan. |
DOI | 10.1016/j.jiac.2016.06.010 |
PMID | 27452428 |