教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Prevalence of irritable bowel syndrome - like symptoms in Japanese patients with inactive inflammatory bowel disease. |
掲載誌名 | 正式名:Journal of neurogastroenterology and motility 略 称:J Neurogastroenterol Motil ISSNコード:2093-0879(Print)2093-0879(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 22(4),pp.661-9 |
著者・共著者 | Tomita Toshihiko, Kato Yuu, Takimoto Mayumi, Yamasaki Takahisa, Kondo Takashi, Kono Tomoaki, Tozawa Katsuyuki, Yokoyama Yoko, Ikehara Hisatomo, Ohda Yoshio, Oshima Tadayuki, Fukui Hirokazu, Tanaka Shigemi, Shima Masayuki, Watari Jiro, Miwa Hiroto |
発行年月 | 2016/05 |
概要 | Background/Aims:Few studies are available that investigated the risk factor for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive Inflammatory bowel disease (IBD). The present study had 3 objectives: (1) to assess the prevalence of IBS-like symptoms in Japanese patients with inactive IBD using Rome III criteria, (2) to examine the relationship of IBS-like symptoms to health related quality of life (HR-QOL), and (3) to investigate associations for developing IBS-like symptoms in patients with inactive IBD.Methods:IBS-like symptoms were evaluated using the Rome III questionnaire for functional gastrointestinal disorders. HR-QOL and hospital anxiety and depression scale were evaluated.Results:IBS-like symptoms were found in 17.5% (7/40) of patients with inactive ulcerative colitis, 27.1% (29/107) of patients with inactive Crohn's disease (CD), and 5.3% (23/438) of healthy control subjects. The QOL level was significantly lower and anxiety score was significantly higher in inactive CD patients with IBS-like symptoms than in those without such symptom (P = 0.003, P = 0.009). Use of anti-anxiety drugs was associated with the presence of IBS symptoms (P = 0.045). HR-QOL score was lower and anxiety score was higher in patients with inactive ulcerative colitis, but the difference was not statistically significant.Conclusions:The prevalence of IBS-like symptoms in inactive IBD patients was significantly higher than in healthy controls. Inactive CD patients with IBS-like symptoms has low QOL and anxiety; suggesting that anxiety may be associated with symptom development in such patients. |
DOI | 10.5056/jnm15160 |
PMID | 27193973 |