教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Intravascular Ultrasound-Derived Stent Dimensions as Predictors of Angiographic Restenosis Following Nitinol Stent Implantation in the Superficial Femoral Artery. |
掲載誌名 | 正式名:Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 略 称:J Endovasc Ther ISSNコード:1545-1550(Electronic)1526-6028(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 23(3),pp.424-32 |
著者・共著者 | Miki Kojiro, Fujii Kenichi, Kawasaki Daizo, Shibuya Masahiko, Fukunaga Masashi, Imanaka Takahiro, Tamaru Hiroto, Sumiyoshi Akinori, Nishimura Machiko, Horimatsu Tetsuo, Saita Ten, Okada Kozo, Kimura Takumi, Honda Yasuhiro, Fitzgerald Peter J, Masuyama Tohru, Ishihara Masaharu |
発行年月 | 2016/06 |
概要 | PURPOSE:To identify intravascular ultrasound (IVUS) measurements that can predict angiographic in-stent restenosis (ISR) following nitinol stent implantation in superficial femoral artery (SFA) lesions.METHODS:A retrospective review was conducted of 97 patients (mean age 72.9±8.9 years; 63 men) who underwent IVUS examination during endovascular treatment of 112 de novo SFA lesions between July 2012 and DecemMETHODS:ber 2014. Self-expanding bare stents were implanted in 46 lesions and paclitaxel-eluting stents in 39 lesions. Six months after stenting, follow-up angiography was conducted to assess stent patency. The primary endpoint was angiographic ISR determined by quantitative vascular angiography analysis at the 6-month follow-up. Variables associated with restenosis were sought in multivariate analysis; the results are presented as the odds ratio (OR) and 95% confidence interval (CI).RESULTS:At follow-up, 27 (31.8%) angiographic ISR lesions were recorded. The lesions treated with uncoated stents were more prevalent in the ISR group compared with the no restenosis group (74.1% vs 44.8%, p=0.02). Lesion length was longer (154.4±79.5 vs 109.0±89.3 mm, p=0.03) and postprocedure minimum stent area (MSA) measured by IVUS was smaller (13.9±2.8 vs 16.3±1.6 mm(2), pRESULTS:<RESULTS:0.001) in the ISR group. Multivariate analysis revealed that bare stent use (OR 7.11, 95% CI 1.70 to 29.80, pRESULTS:<RESULTS:0.01) and longer lesion length (OR 1.08, 95% CI 1.01 to 1.16, p=0.04) were predictors of ISR, while increasing postprocedure MSA (OR 0.58, 95% CI 0.41 to 0.82, pRESULTS:<RESULTS:0.01) was associated with lower risk of ISR. Receiver operating characteristic analysis identified a MSA of 15.5 mm(2) as the optimal cutpoint below which the incidence of restenosis increased (area under the curve 0.769).CONCLUSION:Postprocedure MSA can predict ISR in SFA lesions, which suggests that adequate stent enlargement during angioplasty might be required for superior patency. |
DOI | 10.1177/1526602816641669 |
PMID | 27044270 |