教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Correlation between olfactory acuity and sinonasal radiological findings in adult patients with chronic rhinosinusitis. |
掲載誌名 | 正式名:Auris, nasus, larynx 略 称:Auris Nasus Larynx ISSNコード:1879-1476(Electronic)0385-8146(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 43(4),pp.422-8 |
著者・共著者 | Saito Takahiro, Tsuzuki Kenzo, Yukitatsu Yoriko, Sakagami Masafumi |
発行年月 | 2016/08 |
概要 | OBJECTIVE:This study aimed to clarify the correlation between olfactory disorder severity and radiological findings in patients with chronic rhinosinusitis (CRS) in the preoperative stage.METHODS:From 2007 to 2014, 272 adult patients (163 men, 109 women; age range 22-80 years) with olfactory disorder due to bilateral CRS who were scheduled to undergo primary endoscopic sinus surgery (ESS) were enrolled. Two groups were studied: eosinophilic CRS (ECRS,METHODS:n=193); and non-ECRS (n=79). TMETHODS:&METHODS:T olfactometer recognition and intravenous olfaction tests were used. Computed tomography (CT) scores for sinuses and olfactory clefts (OC) were applied. Correlations between olfactory acuity and CT score were statistically analysed.RESULTS:In both groups, recognition threshold correlated significantly with CT score. Recognition threshold and CT score were significantly more severe in ECRS than in non-ECRS. CT score at OC showed the strongest correlation with recognition threshold. CT scores for total sinuses and OC in patients showing a positive response to the intravenous olfaction test (239 patients) were significantly milder than those in the negative group (29 patients), but ethmoid CT score was not.CONCLUSION:Olfactory disorder severity correlated significantly with CT opacification. Olfactory disorder and CT findings were more severe in patients with ECRS than in those with non-ECRS. |
DOI | 10.1016/j.anl.2015.12.007 |
PMID | 26743838 |