教員業績データベース |
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論文種別 | 症例報告 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | Efficacy of Intrathecal MTX/Ara-C Combined with Systemic Chemotherapy in a Gastric Cancer Patient with Meningeal Carcinomatosis. |
掲載誌名 | 正式名:Internal medicine (Tokyo, Japan) 略 称:Intern Med ISSNコード:1349-7235(Electronic)0918-2918(Linking) |
掲載区分 | 国内 |
巻・号・頁 | 55(6),pp.609-11 |
著者・共著者 | Yamasaki Takahisa, Fukui Hirokazu, Sei Hiroo, Hara Ken, Eda Hirotsugu, Kondo Takashi, Toyoshima Fumihiko, Kono Tomoaki, Tozawa Katsuyuki, Ikehara Hisatomo, Tomita Toshihiko, Oshima Tadayuki, Watari Jiro, Miwa Hiroto |
発行年月 | 2016/03 |
概要 | A 35-year-old man was diagnosed to have gastric cancer by endoscopic and histological examinations. Staging laparoscopy detected peritoneal metastasis. Systemic chemotherapy was started, but the patient complained of severe headache. Subsequently, a lumbar puncture demonstrated adenocarcinoma cells in the spinal fluid, suggesting the occurrence of meningeal carcinomatosis (MC) from gastric cancer. MC occurs only rarely in patients with gastric cancer, but the prognosis is invariably poor. However, this patient nevertheless survived for 12 months after receiving intrathecal MTX/Ara-C together with systemic chemotherapy. Therefore, the early detection of meningeal irritation sign and intrathecal chemotherapy might greatly improve the prognosis of gastric cancer patients with MC. |
DOI | 10.2169/internalmedicine.55.5129 |
PMID | 26984076 |