Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Outcome assessment of hemiparesis due to intracerebral hemorrhage using diffusion tensor fractional anisotropy. |
Journal | Formal name:Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association Abbreviation:J Stroke Cerebrovasc Dis ISSN code:1532-8511(Electronic)1052-3057(Linking) |
Volume, Number, Page | 24(4),pp.881-9 |
Papers・Author | Koyama Tetsuo, Marumoto Kohei, Uchiyama Yuki, Miyake Hiroji, Domen Kazuhisa |
Publication date | 2015/04 |
Papers・Description | BACKGROUND:This study aimed to evaluate the prognostic efficacy of magnetic resonance diffusion tensor fractional anisotropy (FA) for patients with hemiparesis due to intracerebral hemorrhage.METHODS:Diffusion tensor FA brain images were acquired 14-21 days after putaminal and/or thalamic hemorrhage. The ratio of FA values within the cerebral peduncles of the affected and unaffected hemispheres (rFA) was calculated for each patient (n = 40) and assessed for correlation with Brunnstrom stage (BRS, 1-6), motor component of the functional independence measure (FIM-motor, 13-91), and the total length of stay (LOS) until discharge from rehabilitation (P METHODS:<METHODS: .05). Ordinal logistic regression analyses were conducted to determine the relationships between rFA and specific outcomes as measured by BRS range (poor, BRS 1 or 2; moderate, BRS 3 or 4; and good, BRS 5 or 6; P METHODS:<METHODS: .05).RESULTS:The rFA values were .571-1.043 (median, .856) and BRS scores were 1-6 (median, 4) for shoulder/elbow/forearm, 1-6 (median, 4) for hand, and 2-6 (median, 4) for lower extremities. FIM-motor scores were 58-86 (median, 78) and LOS ranged from 42 to 225 days (median, 175.5 days). Correlation coefficients were statistically significant between rFA and shoulder/elbow/forearm BRS (.696), hand BRS (.779), lower extremity BRS (.631), FIM-motor (.442), and LOS (-.598). Logistic model fit was moderate for shoulder/elbow/forearm BRS (R(2) = .221) and lower extremity BRS (R(2) = .277), but was much higher for hand BRS (R(2) = .441).CONCLUSIONS:Diffusion tensor FA values are predictive of clinical outcome from hemiparesis due to putaminal and/or thalamic hemorrhage, particularly hand function recovery. |
DOI | 10.1016/j.jstrokecerebrovasdis.2014.12.011 |
PMID | 25724241 |