Faculty Information |
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Article types | Original article |
Language | English |
Refereed paper | Refereed |
Title | Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases. |
Journal | Formal name:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Abbreviation:J Infect Chemother ISSN code:1437-7780(Electronic)1341-321X(Linking) |
Volume, Number, Page | 21(9),pp.623-33 |
Papers・Author | Ishikawa Kiyohito, Hamasuna Ryoichi, Uehara Shinya, Yasuda Mitsuru, Yamamoto Shingo, Hayami Hiroshi, Takahashi Satoshi, Matsumoto Tetsuro, Minamitani Shinichi, Kadota Jun-ichi, Iwata Satoshi, Kaku Mitsuo, Watanabe Akira, Sunakawa Keisuke, Sato Junko, Hanaki Hideaki, Tsukamoto Taiji, Kiyota Hiroshi, Egawa Shin, Deguchi Takashi, Matsumoto Minori, Tanaka Kazushi, Arakawa Soichi, Fujisawa Masato, Kumon Hiromi, Kobayashi Kanao, Matsubara Akio, Wakeda Hironobu, Amemoto Yoshinosuke, Onodera Shoichi, Goto Hirokazu, Komeda Hisao, Yamashita Masuo, Takenaka Tadasu, Fujimoto Yoshinori, Tsugawa Masaya, Takahashi Yoshito, Maeda Hiroshi, Onishi Hiroyuki, Ishitoya Satoshi, Nishimura Kazuo, Mitsumori Kenji, Ito Toru, Togo Yoshikazu, Nakamura Ichiro, Ito Noriyuki, Kanamaru Sojun, Hirose Takaoki, Muranaka Takashi, Yamada Daisuke, Ishihara Satoshi, Oka Hiroya, Inatomi Hisato, Matsui Takashi, Kobuke Makoto, Kunishima Yasuharu, Kimura Takahiro, Ichikawa Takaharu, Kagara Ichiro, Matsukawa Masanori, Takahashi Koichi, Mita Koji, Kato Masao, Okumura Kazuhiro, Kawanishi Hiroaki, Hashimura Takayuki, Aoyama Teruyoshi, Shigeta Masanobu, Koda Shuntaro, Taguchi Keisuke, Matsuda Yohei. |
Publication date | 2015/09 |
Papers・Description | To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy, the Japanese Association of Infectious Disease, and the Japanese Society of Clinical Microbiology conducted the second nationwide surveillance from January to September 2011. With the cooperation of 42 medical institutions throughout Japan, 1036 strains belonging to 8 clinically relevant bacterial species were collected. Among methicillin-resistant Staphylococcus aureus (MRSA) strain, the vancomycin (VCM) MIC for 5.5% (3/55) of the strains was 2 μg/mL. Ampicillin, VCM, and linezolid were relatively active against 209 Enterococcus faecalis strains. The proportion of fluoroquinolone (FQ)-resistant strains was>20%. The MIC90 of FQs against the 382 Escherichia coli strains was 2-64 mg/L and the proportion resistant to FQs was approximately 30%. However, susceptibility of E. coli to sitafloxacin was still high (MIC90 = 2 mg/L). Fifty-eight (15.2%) of 382 E. coli, 6 (4.5%) of 132 Klebsiella pneumoniae, 1 (2.4%) of 41 Klebsiella oxytoca and 4 (6.8%) of 59 Proteus mirabilis strains were suspected of producing extended-spectrum beta-lactamase. Of 93 Pseudomonas aeruginosa strains, the proportions resistant to imipenem, amikacin, and ciprofloxacin were 21.5%, 4.3%, and 20.4%, respectively. Four strains (4.3%) were found to be multidrug-resistant. In complicated UTI cases, all of MRSA and E. faecalis were susceptible to all anti-MRSA agents. Sitafloxacin was active against other FQ-resistant E. coli strains. The isolation of extended-spectrum beta-lactamase-producing and multidrug-resistant strains increased. |
DOI | 10.1016/j.jiac.2015.05.014 |
PMID | 26166322 |