教員業績データベース |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | A large-scale, prospective, observational study of leukocytapheresis for ulcerative colitis: treatment outcomes of 847 patients in clinical practice. |
掲載誌名 | 正式名:Journal of Crohn's&colitis 略 称:J Crohns Colitis ISSNコード:1876-4479(Electronic)1873-9946(Linking) |
巻・号・頁 | 8(9),pp.981-91 |
著者・共著者 | Yokoyama Yoko, Matsuoka Katsuyoshi, Kobayashi Taku, Sawada Koji, Fujiyoshi Tateshi, Ando Takafumi, Ohnishi Yoshifumi, Ishida Tetsuya, Oka Masashi, Yamada Masahiro, mura Takashi, Ino Tomoko, Numata Toyoko, Aoki Hirofumi, Sakou Jun-Ichi, Kusada Masahiro, Maekawa Tomoki, Hibi Toshifumi |
発行年月 | 2014/09 |
概要 | BACKGROUND AND AIMS:Leukocytapheresis is an extracorporeal therapy for ulcerative colitis. However, no large-scale study on leukocytapheresis has been reported. This large-scale, prospective, observational study aimed to evaluate the treatment outcomes of leukocytapheresis for active ulcerative colitis in clinical practice.METHODS:Patients with active ulcerative colitis treated with leukocytapheresis using a Cellsorba E column between May 2010 and December 2012 were enrolled from 116 medical facilities in Japan.RESULTS:A total of 847 patients were enrolled, and 623 were available for efficacy analysis. Out of 847 patients, 80.3% of the patients had moderate to severe disease activity, and 67.6% were steroid refractory. |
DOI | 10.1016/j.crohns.2014.01.027 |
PMID | 24556083 |