教員業績データベース |
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論文種別 | 総説 |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | Diffuse gastroduodenitis and enteritis associated with ulcerative colitis and concomitant cytomegalovirus reactivation after total colectomy: report of a case. |
掲載誌名 | 正式名:Surgery today 略 称:Surg Today ISSNコード:1436-2813(Electronic)0941-1291(Linking) |
巻・号・頁 | 43(3),pp.321-4 |
著者・共著者 | Uchino Motoi, Ikeuchi Hiroki, Bando Toshihiro, Matsuoka Hiroki, Hirata Akihiro, Takahashi Yoshiko, Takesue Yoshio, Inoue Satoko, Tomita Naohiro |
発行年月 | 2013/03 |
概要 | Wereport a rare case of peristomal pyoderma gangrenosum with severe gastroduodenal lesions, developing after total colectomy in a patient with ulcerative colitis and concomitant cytomegalovirus (CMV) enteritis. A 19-year-old man underwent total proctocolectomy with an ileal J-pouch anal anastomosis and diverting ileostomy, after 2 years of ineffective medical treatment. On postoperative day 6, severe peristomal pyoderma gangrenosum developed and progressed rapidly. Maintaining immunosuppressive therapy with corticosteroids for 6 days induced melena from the gastroduodenal lesions and enteritis with concomitant CMV reactivation. The patient required a jejunostomy, after the duodenal and intestinal CMV lesions had caused multiple perforations. Treatment with intensive cytapheresis was ineffective against the associated UC lesions, which healed with infliximab induction. The CMV reactivation was treated effectively with ganciclovir. The patient is being maintained on infliximab every 8 weeks and there has been no sign of recurrence of the gastroduodenitis-associated UC and CMV reactivation. |
DOI | 10.1007/s00595-012-0329-z |
文献番号 | 22965486 |