Shibahara Hiroaki Department
Specialty Division
Obstetrics and Gynecology, Clinical Medicine Seminars
Position
■ Journal
1.
Introduction
Methods for direct and indirect antisperm antibody testing 2013/01
2.
Case report
Long-term disease-free survival after radical local excision of low-grade myofibroblastic sarcoma of the vulva. 2013/04
3.
Case report
A case of primary metastatic glassy cell carcinoma of the uterine cervix that responded to combined docetaxel and carboplatin. 2013/07
4.
Original article
Live births from isolated primary/early secondary follicles following a multistep culture without organ culture in mice. 2013/07
5.
Original article
Prognostic factors for locally advanced cervical cancer treated with neoadjuvant intravenous and transuterine arterial chemotherapy followed by radical hysterectomy 2013/10
6.
Original article
Development of an integrated support system for hereditary cancer and its impact on gynecologic services. 2013/12
7.
Original article
Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males 2013/12
8.
Introduction
Infertility and immunocontraception based on zona pellucida. 2014/01
9.
Original article
Benefit of palliative chemotherapy and hospice enrollment in late-stage ovarian cancer patients. 2014/05
10.
Original article
Feasibility and efficacy of intraperitoneal docetaxel administration as salvage chemotherapy for malignant gynaecological ascites. 2014/07
11.
Original article
Expression of Chemokine Ligand 18 in Stage IA Low-grade Endometrial Cancer. 2014/10
12.
Case report
Complete remission achieved by oophorectomy for recurrent endometrial stromal sarcoma after laparoscopic morcellation. 2014/11
13.
Original article
Development of an integrated support system for hereditary cancer and its impact on gynecologic services. 2014/12
14.
Original article
Methylation progress of mouse maternal imprinted gene, LIT1 and Zac1 in primary follicles under in-vitro conditions. 2015/02
15.
Original article
Mitochondrial DNA copy number in cumulus cells is a strong
predictor of obtaining good-quality embryos after IVF 2015/12
16.
Case report
Bevacizumab helped resolve pericardial and pleural effusion that was associated with malignant ovarian clear cell carcinoma 2016/01
17.
Original article
Expression of Hedgehog Signals and Growth Inhibition
by Itraconazole in Endometrial Cancer 2016/01
18.
Original article
Gremlin 2 is Repressed in Invasive Endometrial Cancer
and Inhibits Cell Growth In Vitro 2016/01
19.
Case report
Pazopanib-mediated long-term disease stabilization after resection of a uterine leiomyosarcoma metastasis 2016/01
20.
Research report
The present status of certified"embryologists of assisted reproductive technology" in Japan 2015 2016/04
21.
Original article
Effects of gremlin-2 on the transition of primordial follicles during
early folliculogenesis in the human ovary 2016/05
22.
Original article
Itraconazole Inhibits AKT/mTOR Signaling and Proliferation in Endometrial Cancer Cells. 2017/02
23.
Introduction
Repurposing itraconazole as an anticancer agent (Review) 2017/04
24.
Original article
Quantitative and qualitative changes of mitochondria in human preimplantation embryos 2017/05
25.
Original article
Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells 2017/07
26.
Original article
Fertility Preservation for Adolescent and Young Adult Women in Hyogo College of Medicine College Hospital 2017/09
27.
Original article
Expression of natural cytotoxicity receptors and cytokine production on endometrial natural killer cells in women with recurrent pregnancy loss or implantation failure, and the expression of natural cytotoxicity receptors on peripheral blood natural killer cells in pregnant women with a history of recurrent pregnancy loss. 2017/11
28.
Introduction
The current perspectives on the mammalian zona pellucida. 2017/12
29.
Case report
A Case of a Pregnant Woman with Thrombosis in an Artificial Aortic Valve Resulting in Severe Cerebral Hemorrhage in the Newborn 2018/01
30.
Case report
Pazopanib treatment of a platinum-resistant recurrence of a high-grade
Sertoli cell tumor and assessment of the treatment response by FDG-PET/CT:
A case report 2018/01
31.
Original article
Status of ovarian tissue cryopreservation for adolescent and young adult patients with cancer in Hyogo College of Medicine College Hospital. 2018/01
32.
Case report
Adolescent bladder endometriosis initially diagnosed as premenarchal disease: a case report and review of the literature 2018/03
33.
Case report
Bevacizumab with metronomic chemotherapy of low-dose oral
cyclophosphamide in recurrent cervical cancer: Four cases 2018/04
34.
Original article
Fertility preservation and pregnancy outcomes in adolescent and young adult male patients with cancer. 2018/10
35.
Original article
Effects of leuprorelin for the treatment of recurrent gynecological cancer by assessment including self-administered quality-of-life questionnaire 2019/01
36.
Case report
Resuscitative hysterotomy in a patient with peripartum
cardiomyopathy 2019/03
37.
Case report
Removal of a Retroperitoneal Foreign Body by Laparoscopic Surgery. 2019/04
38.
Original article
Challenges in Managing Patients with Hereditary Cancer at Gynecological Services 2019/05
39.
Original article
Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis. 2019/08
40.
Case report
Association Between Spontaneous Ovulation and Serum anti-Müllerian Hormone Levels in a Premature Ovarian Insufficiency Patient After a Multimodal Treatment for Breast Cancer 2019/11
41.
Original article
Effects of 5-hydroxytrypyamine on spermatozoal hyperactivation and in vitro fertilization in mice. 2019/11
42.
Original article
Paternal occupational exposure to chemicals and secondary sex ratio: results from the Japan Environment and Children's Study. 2019/12
43.
Original article
Mitochondrial oxygen consumption rate of human embryos declines with maternal age 2020/09
44.
Original article
Prevention and practice during the COVID-19 emergency declaration period in Japanese obstetrical/gynecological facilities 2020/09
45.
Introduction
Anti-sperm antibodies and reproductive failures 2021/04
46.
Original article
Co-expression of NKp46 with activating or inhibitory receptors on, and cytokine production by, uterine endometrial NK cells in recurrent pregnancy loss 2021/04
47.
Original article
Pelvic endometriosis and natural killer cell immunity 2021/04
48.
Original article
Association between the serum insulin-like growth factor-1 concentration in the first trimester of pregnancy
and postpartum depression 2021/05
49.
Original article
Association between the serum insulin-like growth factor-1 concentration in the first trimester of pregnancy and postpartum depression. 2021/05
50.
Original article
Sperm immobilization test and quantitative sperm immobilization test using frozen-thawed sperm preparation applied with computer-aided sperm analysis 2021/05
51.
Case report
The chronological change in transvaginal ultrasound images of a hemorrhagic ovarian cyst observed during infertility treatment: A case report and literature review 2021/07
52.
Original article
Feelings about pregnancy and mother-infant bonding as predictors of persistent psychological distress in the perinatal period: The Japan Environment and Children's Study. 2021/08
53.
Original article
Itraconazole increases resolvin E3 concentration and 12/15-lipoxygenase inhibitor attenuates its anticancer activity in cervical cancer cells 2021/09
54.
Original article
NK cells that differ in expression of NKp46 might play different roles in endometrium 2021/09
55.
Original article
Itraconazole Inhibits Intracellular Cholesterol Trafficking and Decreases Phosphatidylserine Level in Cervical Cancer Cells 2021/11
56.
Original article
Creation, effects on embryo quality, and clinical outcomes of a new embryo culture medium with 31 optimized components derived from human oviduct fluid: A prospective multicenter randomized trial 2022/04
57.
Introduction
Sex difference in anti-sperm antibodies 2022/04
58.
Original article
Evaluation of NKp46 expression and cytokine production of decidual NK cells in women with recurrent pregnancy loss 2022/06
59.
Original article
Antisperm antibodies and reproductive failure 2022/07
60.
Original article
Natural killer cell pathology and repeated implantation failures 2022/07
61.
Original article
Association of epidural analgesia during labor with neurodevelopment of children during the first three years: the Japan Environment and Children’s Study 2022/09
62.
Case report
Extraskeletal Myxoid Chondrosarcoma of the Vulva: A Case Report 2023/01
63.
Original article
Impact of the COVID-19 pandemic on surgery for benign diseases in gynecology: A nationwide survey by the Japan Society of Obstetrics and Gynecology 2023/01
64.
Original article
Co-expression of activating and inhibitory receptors on peritoneal fluid NK cells in women with endometriosis 2023/02
65.
Original article
Itraconazole Repolarizes Tumor-associated Macrophages and Suppresses Cervical Cancer Cell Growth 2023/02
66.
Original article
Itraconazole Modulates Phospholipid Levels in Tumor-associated Macrophages 2023/03
67.
Original article
Analyzing the relationship between feelings about pregnancy and mother-infant bonding with the onset of maternal psychological distress after childbirth: The Japan Environment and Children's Study 2023/05
68.
Original article
Comprehensive Genomic Profiling Detects Hereditary Cancers and Confers Survival Advantage in Patients With Gynaecological Cancers 2023/05
69.
Original article
Characterization of a spontaneously occurring self-reactive antibody to sperm in mice. 2023/06
70.
Original article
Medroxyprogesterone as the Initial Systemic Treatment of Recurrent Endometrial Cancer: A Single Institutional Study 2023/06
71.
Original article
Weight‑Loss Interventions and Levonorgestrel Intrauterine System Implantation for Early‑Stage Endometrial Cancer and Atypical Endometrial Hyperplasia to Reduce Perioperative Risk of Severely Obese Patients 2023/07
72.
Case report
Fertility-sparing management of stage IIIC serous borderline ovarian tumor: A case report of a 20-year follow-up 2023/11
Sperm Immobilizing Antibody and Its Target Antigen, Immune Infertility 2017/01
■ Presentation
1.
Identification of a novel sperm-specific protein reacted with sperm-immobilizing antibody from immunologically infertile men. (Poster presentation,General Lecture) 2013/05/28
2.
A case of fetal hypothyroidism recognized during treatment of Basedow disease with oral medicine (Poster presentation,General Lecture) 2013/06/02
3.
Benefit of palliative chemotherapy and hospice enrollment in late-stage ovarian cancer patients (Poster presentation,General Lecture) 2013/10/19
4.
Prognostic factors for cernical cancer treated with neoadjuvant trans-uterine arterial chemotherapy: A single-institution study (Poster presentation,General Lecture) 2013/10/19
5.
Infertile women with lower AMH value due to past history of ovarian surgery have higher chance of successful pregnancy by ART. (Poster presentation,General Lecture) 2013/10/21
6.
Evaluation of the gene expression involved in implantation (Oral presentation,General Lecture) 2013/12/01
7.
Succesful live births from primary or early secondary follicles through multistep in-vitro growth (IVG) followed by in-vitro fertilization and embryo transfer (IVG-ET) in mice (Oral presentation,General Lecture) 2013/12/01
8.
Evaluation of the gene expression in peripheral endometrial carcinoma tissue. (Poster presentation,General Lecture) 2014/05/01
9.
Role of anti-sperm antibodies in immunologically infertile women (Oral presentation,Special/Invited Lecture) 2014/05/23
10.
Development of GVHD therapy using fetal appendage derived MSCs (Oral presentation,General Lecture) 2015/03/06
11.
Expression and localization of hormone receptors and growth factors in the ovarian sections from cynomogus monkeys (Oral presentation,General Lecture) 2015/04/26
12.
ICSI in not necessary for the treatment of immunologically infertile women with sperm immobilizing antibodies (Poster presentation,General Lecture) 2015/04/26
13.
Indvidualized controlled ovarian stimulation (iCOS)and luteal support for ART (Oral presentation) 2015/04/26
14.
Management and complications of pregnancies after egg donation in our hosptal (Poster presentation,General Lecture) 2015/04/26
15.
Immunocytochemical study of ovarian hormone receptors and factors in non-human primate (Macaca Fascicularis) (Poster presentation,General Lecture) 2015/05/22
16.
Profiling of gene expression during early folliculogenesis in mice. (Poster presentation,General Lecture) 2015/05/22
17.
Expression of Hedgehog signals and growth inhibition by itraconazole in endomertial (Poster presentation,General Lecture) 2016/04/16
18.
Gremlin2 is repressed in invasive endometrial cancer and inhibits cell growth in vitro (Poster presentation,General Lecture) 2016/04/16
19.
A three year experience of fertility preservation for AYA women (Poster presentation,General Lecture) 2016/05/21
20.
Presence and possible function of Gremlin2 in the human ovary (Poster presentation,General Lecture) 2016/05/21
21.
Analysis of sperm immobilization by complement-dependent sperm immobilizing antibody using computer-aided sperm analysis (CASA) (Poster presentation,General Lecture) 2016/06/22
22.
The role of seminal vesicle fluid on successful embryo implantation for IVF-ET system in mice (Oral presentation,General Lecture) 2016/06/22
23.
The Status of Sperm Immobilizing-Antibody (SI-Ab) detected in Infertile Females (Therapy and Pathogenic Mechanisms) (Poster presentation,General Lecture) 2016/06/22
24.
Repositioning itraconazole as an anticancer drug for endometrial cancer (Oral presentation,General Lecture) 2016/07/09
25.
Analysis of four cases of unexpected NIPT results; false positive, false-negative and non-reportable cases (Poster presentation,General Lecture) 2016/07/10
26.
Radiographic pelvimetry: evaluation of radiation dose and image quality (Poster presentation,General Lecture) 2016/07/10
27.
Development of a safe and effective cryoprotectant for ovarian cryopreservation (Poster presentation,General Lecture) 2016/11/18
28.
Experience of fertility preservation in male cancer patients (Oral presentation,Special/Invited Lecture) 2016/11/18
29.
Fertility preservation for adolescent and young adult women (Poster presentation,General Lecture) 2016/11/18
30.
A fetus with lethal chromosomal abnormality lead to a spontaneous abortion in the first trimester (Poster presentation,General Lecture) 2017/06/15
31.
Development of a regional oncofertility network for fertility preservation in AYA patients: one-year experience (Poster presentation,General Lecture) 2017/06/15
32.
Possible molecular mechanism for infertility in women caused by sperm immobilizing antibody(Sl-Ab) (Oral presentation,Special/Invited Lecture) 2017/09/07
33.
A strategy for the treatment of infertile woman with sperm immobilizing antibody in their sera (Poster presentation,General Lecture) 2017/09/17
NK cells and reproduction our progress in NK cell study (Oral presentation,General Lecture) 2017/09/17
36.
The co-expression of activating and inhibitory receptors and cytokines production for uterine NK cells (Oral presentation,General Lecture) 2017/09/17
37.
Regulation of rodent sperm hyperactivation by serotonin (Poster presentation,General Lecture) 2017/09/28
38.
Fertility preservation in male AYA patients with cancer (Oral presentation,Special/Invited Lecture) 2017/10/14
39.
A successful pregnancy in a patient with 46,XY pure gonadal dysgenesis after transfer of a frozen-thawed embryo derived from donor oocytes (Poster presentation,General Lecture) 2018/05/11
40.
Application of Compute-Aided Sperm Analysis (CASA) for Sperm Immobilization Test (Poster presentation,General Lecture) 2018/05/11
41.
Fertility preservation by ovarian tissue cryopreservation for adolescent and young adult patients in our department (Oral presentation,General Lecture) 2018/05/11
42.
Repurposing itraconazole as an anticancer agent : rapid clinical response of metastatic vaginal melanoma (Poster presentation,General Lecture) 2018/05/11
43.
Vulvar apocrine adenocarcinoma responded to weekly paclitaxel and biweekly bevacizumab. A case report (Poster presentation,General Lecture) 2018/05/11
44.
NK cell abnormality and its treatment in women with reproductive failure (Oral presentation,Symposium/Workshop/Panel Discussion) 2018/06/15
45.
Successful pregnancy in a case of repeated implantation failure(RIF) due to elevated Th1/Th2 using intravenous immunoglobulin treatment(IVIG) (Poster presentation,General Lecture) 2018/06/28
46.
The co-expression of activating and inhibitory receptors and cytokines production for uterine NK cells (Poster presentation,General Lecture) 2018/06/28
47.
Cytokaines production and co-expression of activating and inhibitory receptors of uterine NK cells in RPL (Poster presentation,General Lecture) 2019/06/11
48.
Mouse ovarian culture using meshes and evaluation of follicular development (Poster presentation,General Lecture) 2019/10/24
49.
Cytokines production and co-expression of activating and inhibitory receptors of uterine NK cells in woman with RPL (Poster presentation,General Lecture) 2019/11/13
50.
His research on anti-sperm antibody (Oral presentation) 2019/11/13
51.
In regards to different density of CD16 on NK cells, are they play different role in reproductive outcome? (Poster presentation,General Lecture) 2019/11/13
52.
The expression of NKp46 on uterine NK cells and Cytokines Production by NK cells in women with recurrent Pregnancy loss (Poster presentation,General Lecture) 2019/11/13
53.
Do NKp46dim and NKp46bright receptors play different role in reproduction? (Web announcement,General Lecture) 2020/04/24
54.
Genomic profiling of primary peritoneal cancer with platinum sensitive recurrence. A two cases (Web announcement,General Lecture) 2020/04/24
55.
The chronological change of the transvaginal ultrasound images of a hemorrhagic ovarian cyst (Web announcement,General Lecture) 2020/04/24
56.
The precise ovarian volume is significantly associated with circulating levels of AMH, the ratio of LH/FSH and total testosterone concentrations (Web announcement,General Lecture) 2020/04/24
57.
Metronomic chemotherapy using oral cyclophosphamide and bevacizumab (mCPA-BEV) for recurrent cervical cancer (Web announcement,General Lecture) 2020/04/25
58.
A long-team response to olaparib in a germline BRCA mutated patient with uterine serous carcinoma : A case report (Web announcement,General Lecture) 2020/04/26
59.
CO-EXPRESSION OF ACTIVATING AND INHIBITORY RECEPTORS ON PERITONEAL FLUID NK CELLS IN WOMEN WITH ENDOMETRIOSIS. (Web announcement,General Lecture) 2020/10/17
60.
Characterization of spontaneously occurred IgA antibody against sperm (Web announcement,General Lecture) 2021/04/10
61.
Our challenge to increase the success rate for hysteroscopically assisted falloposcopic tuboplasty (Web announcement,General Lecture) 2021/04/24
62.
Anti-Mullerian hormone (AMH) as an ovarian reserve marker in cancer patients who undergo ovarian tissue cryopreservation (Web announcement,General Lecture) 2021/04/25
63.
Bevacizumab with metronomic oral cyclophosphamide for patients with recurrent cervical cancer (Web announcement,General Lecture) 2021/04/25
64.
In regards to different fluorescence density of NKp46 on NK cells, are they play different role in reproductive outcome? (Web announcement,General Lecture) 2021/04/25
65.
Rapid response to itraconazole and transcript analysis of the cervical cancer tissue obtained by the sequential biopsy: A case report (Web announcement,General Lecture) 2021/04/25
66.
Resolvin E3 : The mechanism of anti-cancer effect of itraconazole in cervical cancer (Web announcement,General Lecture) 2021/04/25
67.
Co-expression of activating and inhabitory receptors on peritoneal fluid NK cells in women with endometriosis (Web announcement,General Lecture) 2021/05
68.
The roles of NKp46 and CD16 on NK cells in reproduction (Web announcement,General Lecture) 2021/05
69.
Fertility preservation in an infant with cerebellar medulloblastoma (Oral presentation,General Lecture) 2021/09/11
70.
Reproductive outcome of septate uterus after hybrid hysteroscopic metroplasty (Oral presentation,General Lecture) 2021/09/11
71.
Safe and affective hysteroscopically and fluoroscopically assisted falloposcopic tuboplasty for women with tubal infertility (Oral presentation,Symposium/Workshop/Panel Discussion) 2021/09/12
72.
Immunopathology and treatment of PCOS (Oral presentation,Symposium/Workshop/Panel Discussion) 2022/05/22
73.
Analysis of the Sperm-Immobilization Phenomenon by Sperm-Immobilizing Antibodies Using CASA (Poster presentation,General Lecture) 2022/08/05
74.
Case reports of obese endometrial cancer patients with levonorgestrel IUS to reduce the risk of laparoscopic surgery (Poster presentation,General Lecture) 2022/08/05
75.
Characterization of spontaneously-occurring self-reactive antibody to sperm in mine (Poster presentation,General Lecture) 2022/08/05
76.
Effects of serotonin on Human Sperm Functions (Poster presentation,General Lecture) 2022/08/05
77.
Evaluation of ovarian reserve after chemotherapy (Poster presentation,General Lecture) 2022/08/05
78.
Itraconazole inhibits intracellular cholesterol trafficking and decreasesphosphatidylserine level in cervical cancer cells (Poster presentation,General Lecture) 2022/08/05
79.
A case report of multilocus inherited neoplasia alleles syndrome (MINAS) with simultaneous Lynch syndrome and HBOC (Poster presentation,General Lecture) 2022/08/06
80.
Fertility preservation by ovarian tissue cryopreservation for pediatric cancer patients in our department (Poster presentation,General Lecture) 2022/08/06
81.
Itraconazole repolarizes tumor-associated macrophages and suppresses cervical cancer growth (Poster presentation,General Lecture) 2022/10/22
82.
Co-expression of activating and inhibitory receptors on peritoneal fluid NK cells differs betweem deep endometriosis and peritoneal endometriosis (Poster presentation,General Lecture) 2022/10/25
83.
VALIDATION OF DECELLULARIZATION OF FROZEN-THAWED MOUSE OVARIAN TISSUE (Oral presentation,General Lecture) 2022/11/12
84.
Expression of cell adhesion molecules on peripheral blood NK cells in recurrent pregnancy losses (Oral presentation,General Lecture) 2023/04/08
85.
A casa of hypervascular retained products of conception with neo-vascular lesion afterbortion (Poster presentation,General Lecture) 2023/05/12
86.
A case of non-Hodgkin lymphoma of the upper gingiva with minimal residual disease detected ovarian tissue (Poster presentation,General Lecture) 2023/05/12
87.
Expression of ell adhesion molecules on peripheral blood NK cells in recurrent pregnancy losses (Poster presentation,General Lecture) 2023/05/12
88.
Extraskeletal Myxoid Chondrosarcoma (EMC) of the Vulva (Poster presentation,General Lecture) 2023/05/12
89.
Lynch Syndrome (LS) Caused by Rare Intronic Mutation in Mismatch Repair (MMR) Genes : Two Cases (Oral presentation,General Lecture) 2023/07/14
90.
A case of non-Hodgkin lymphoma with minimal residual disease detected in
cryopreserved ovarian tissue without any finding laparoscopically (Oral presentation,General Lecture) 2023/09/15
91.
A study on obtaining mature oocytes through organ culture and follicle development in 3-week-old mice (Poster presentation,General Lecture) 2023/11/02