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    （Last updated : 2023-11-16 14:44:06）
  Nakagomi Takayuki
   Department   Laboratory/Facility  Laboratory of Neurogenesis and CNS Repair, Institute for Advanced Medical Sciences
   Specialty Division  , Endowment Lecture
   Position  
■ Journal
1. Original article　 Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model. 2012/02
2. Original article　 Human umbilical cord provides a significant source of unexpanded mesenchymal stromal cells. 2012/04
3. Original article　 Leptomeningeal-derived doublecortin-expressing cells in poststroke brain. 2012/09
4. Original article　 Glucocorticoid-induced TNF receptor-triggered T cells are key modulators for survival/death of neural stem/progenitor cells induced by ischemic stroke 2012/11
5. Original article　 A highly reproducible model of cerebral ischemia/reperfusion with extended survival in CB-17 mice. 2013/07
6. Original article　 Effect of Cilostazol nanoparticles on endothelial proliferation after ischemic stroke 2014/03
7. Introduction　 Concise Review: Are Stimulated Somatic Cells Truly Reprogrammed into an ES/iPS-Like Pluripotent State? Better Understanding by Ischemia-Induced Multipotent Stem Cells in a Mouse Model of Cerebral Infarction. 2015
8. Introduction　 Leptomeninges: a novel stem cell niche harboring ischemia-induced neural progenitors. 2015/04
9. Original article　 Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells. 2015/06
10. Introduction　 Do Vascular Pericytes Contribute to Neurovasculogenesis in the Central Nervous System as Multipotent Vascular Stem Cells? 2015/08
11. Original article　 Brain pericytes serve as microglia-generating multipotent vascular stem cells following ischemic stroke 2016/03
12. Original article　 Expression patterns and phenotypic changes regarding stemness in brain pericytes in health and disease 2016/06
13. Original article　 Transplantation of hematopoietic stem cells: intra-arterial versus intravenous administration impacts stroke outcomes in a murine model. 2016/10
14. Other　 Leptomeninges: a novel stem cell niche with neurogenic potential. 2017/03
15. Original article　 Identification of Multipotent Stem Cells in Human Brain Tissue Following Stroke. 2017/04
16. Original article　 Induction of Perivascular Neural Stem Cells and Possible Contribution to Neurogenesis Following Transient Brain Ischemia/Reperfusion Injury. 2017/04
17. Original article　 Effect of ADSC-CM on Endogenous Neural Stem Cells Generated after Cerebral Infarction in Mice. 2017/09
18. Introduction　 Novel Regenerative Therapies Based on Regionally Induced Multipotent Stem Cells in Post-Stroke Brains: Their Origin, Characterization, and Perspective. 2017/12
19. Original article　 Ischemic stroke activates the VE-cadherin promoter and increases VE-cadherin expression in adult mice. 2018/05
20. Original article　 Pericyte-derived Bone Morphogenetic Protein 4 Underlies White Matter Damage after Chronic Hypoperfusion. 2018/05
21. Original article　 Comparative Characterization of Ischemia-Induced Brain Multipotent Stem Cells with Mesenchymal Stem Cells: Similarities and Differences. 2018/10
22. Original article　 Isolation and Characterization of Cerebellum-Derived Stem Cells in Poststroke Human Brain. 2019/04
23. Original article　 Adipose-derived stem cell therapy inhibits the deterioration of cerebral infarction by altering macrophage kinetics. 2019/06
24. Introduction　 Neural regeneration by regionally induced stem cells within post-stroke brains: Novel therapy perspectives for stroke patients. 2019/08
25. Original article　 Potential of Adult Endogenous Neural Stem/Progenitor Cells in the Spinal Cord to Contribute to Remyelination in Experimental Autoimmune Encephalomyelitis. 2019/09
26. Original article　 Correlation between radiographic morphometry and body surface somatometry for foot arches 2019/11
27. Original article　 CD44 expression in stem cells and niche microglia/macrophages following ischemic stroke. 2020/03
28. Original article　 Brain pericytes are a major source of lipocalin-type prostaglandin D2 synthase in the cerebral cortex after ischemic stroke 2020/04
29. Original article　 Early reperfusion following ischemic stroke provides beneficial effects, even after lethal ischemia with mature neural cell death 2020/06
30. Introduction　 How long are reperfusion therapies beneficial for patients after stroke onset? Lessons from lethal ischemia following early reperfusion in a mouse model of stroke 2020/08
31. Original article　 Ischemia-induced multipotent stem cells isolated from stroke patients exhibit higher neurogenic differentiation potential than bone marrow-derived mesenchymal stem cells 2020/08
32. Original article　 Epithelioid glioblastoma with microglia features: potential for novel therapy 2020/11
33. Original article　 Voluntary running exercise after focal cerebral ischemia ameliorates dendritic spine loss and promotes functional recovery 2021/05
34. Original article　 Establishment of a Reproducible Ischemic Stroke Model in Nestin-GFP Mice with High Survival Rates. 2021/11
35. Original article　 Bifidobacterium breve during infancy attenuates mobility in low-birthweight rats 2022/04
36. Original article　 Identification of novel multipotent stem cells in mouse spinal cord following traumatic injury 2022/06
37. Original article　 A bore morphogenic protein signaling inhibitor, LDN193189, converts ischemia-induced multipotent stem cells into neural stem/progenitor cell-like cells. 2022/09
38. Other　 A potential new tool to enhance translational success rate in stroke research by backcrossing techniques in transgenic mice 2023/01
39. Original article　 Different contacted cell types contribute to acquiring different properties in brain microglial cells upon intercellular interaction 2023/01
40. Original article　 Enhanced angiogenic properties of umbilical cord blood primed by OP9 stromal cells ameliorates neurological deficits in cerebral infarction mouse model 2023/01
41. Original article　 Transplantation of human brain-derived ischemia-induced multipotent stem cells ameliorates neurological dysfunction in mice after stroke 2023/05
42. Original article　 Microglia negatively regulate the proliferation and neuronal differentiation of neural stem/progenitor cells isolated from post stroke mouse brains. 2023/07
43. Original article　 Microglia Negatively Regulate the Proliferation and Neuronal Differentiation of Neural Stem/Progenitor Cells Isolated from Poststroke Mouse Brains. 2023/08
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■ BooK
1. Contributor　 Ischemia-induced neural　stem/progenitor　cells　within　the　post-stroke　cortex　in　adult　brains, Neural　Stem　Cells　and　Therapy 2012/02
2. Contributor　 Neurogenesis in the cerebral cortex after stroke, Stem Cells and Cancer Stem Cells 2012/03
■ Presentation
1. Cerebral protection effects of lidocaine using transient cortical ischemia model  2012/02
2. Generation of endgenous neural stem cells in the ipsilateral thalamus following cortical infarction （Poster presentation，General Lecture） 2013/06/21
3. Mild ischemic insult promotes neurogenesis in the cerebral cortex （Poster presentation，General Lecture） 2013/06/21
4. Mild ischemic insult promotes neurogenesis in the cerebral cortex. （Oral presentation，General Lecture） 2013/11/02
5. BMP-4 expression by immature pericytes correlates with white matter damage （Poster presentation） 2014/05/21
6. ENDOGENOUS NEUROGENESIS IN POST-STROKE SECONDARY DEGENERATION （Poster presentation，General Lecture） 2014/10/23
7. MILD ISCHEMIC INSULT PROMOTES NEUROGENESIS IN THE CEREBRAL CORTEX （Poster presentation，General Lecture） 2014/10/23
8. NEURAL DIFFERENTIATION OF CD31-POSITIVE CELLS DERIVED FROM CEREBRAL CORTEX IN MOUSE EMBRYO （Poster presentation，General Lecture） 2014/10/23
9. NG2 PROTEOGLYCAN-EXPRESSING CELLS AS MULTIPOTENT STEM CELLS FOLLOWING CEREBRAL INFARCTION （Poster presentation，General Lecture） 2014/10/23
10. Brain Vascular Pericytes Acquire Stemness Following Ischemic Insult （Poster presentation，General Lecture） 2015/04/17
11. Brain pericytes following ischemia acquire neural phenotypes in a mesenchymal-epithelial transition like manner （Oral presentation，General Lecture） 2015/07/30
12. PDGFRβ-expressing brain pericytes following ischemia acquire microglia-generating multipotent stem cell activity. （Poster presentation，General Lecture） 2016/07/20
13. Ischemia-induced multipotent stem cells in human cerebral infarction （Oral presentation，General Lecture） 2018/01/24
14. Brain pericytes following cerebral infarction have more neuronal differentiation potential than bone marrow-derived mesenchymal stem cells （Poster presentation，General Lecture） 2018/06/20
15. Basic characteristics of injury-induced multipotent stem cells in human brains and future prospects （Poster presentation，General Lecture） 2018/06/22
16. : Injury-induced multipotent stem cells; characteristics and future perspective for stroke patients. （Poster presentation，General Lecture） 2018/09/05
17. Potential of cerebellum-derived stem cells in human brain to regenerate functional neurons following ischemic stroke. （Oral presentation，General Lecture） 2019/02/06
18. injury/ischemia-induced multipotent stem cells; iSCs （Oral presentation，Symposium/Workshop/Panel Discussion） 2019/03/21
19. Basic characteristics of injury-induced multipotent stem cells in human brains and future prospects. （Oral presentation，General Lecture） 2019/04/05
20. Brain pericytes after ischemic stroke: a possible role as multipotent stem cells to differentiate into functional neurons. （Poster presentation，General Lecture） 2019/07
21. Possible remyelination by inflammatory-induced endogenous neural stem cells of spinal cord in a mouse model of experimental autoimmune encephalomyelitis. （Poster presentation，General Lecture） 2019/07
22. Cerebellum-derived stem cells obtained from patients with stroke have the potential to differentiate into functional neurons. （Oral presentation，General Lecture） 2019/07/28
23. .Expression of Lipocalin-type Prostaglandin D2 Synthase increase specifically in brain pericytes following Oxygen-Glucose deprivation （Poster presentation，General Lecture） 2020/07
24. CD44 is expressed both in ischemia-induced multipotent stem cells and their niches microglia/macrophages, after ischemic stroke in mice （Poster presentation，General Lecture） 2020/07
25. The identification and future perspectives of ischemia-induced stem cells within post-stroke areas （Oral presentation，Symposium/Workshop/Panel Discussion） 2020/07
26. Novel therapeutic strategies against ischemic stroke from the perspective of neuro-glial-vascular unit―Brain pericytes serve as multipotent stem cells following ischemic stroke （Oral presentation，Symposium/Workshop/Panel Discussion） 2021/05/21
27. Cell density is a key factor for the expansion of ischemia-induced multipotent stem cells （Poster presentation，General Lecture） 2021/07/28
28. Analysis of the phenotypic differences between Nestin-GFP mice genetically derived from C57BL/6 and CB-17 strain mice （Poster presentation，General Lecture） 2022/07
29. Poststroke interaction between SVZ-derived NSPCs and regionally-induced iSCs within the ischemic area （Poster presentation，General Lecture） 2022/07
30. Bifidobacterium breve supplementation during infancy attenuates mobility in low-birthweight rats during adolescence （Poster presentation，General Lecture） 2022/12/07
31. Gap junction protein alpha 1-derived effects against brain microglia differ among the interacted cell types, including endothelial cells, astrocytes, and pericytes （Poster presentation，General Lecture） 2023/08
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