Faculty Information - Shibahara Hiroaki

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JECS Hyogo Unit Center
Center Hyogo Unit of the JECS

（Last updated : 2022-07-02 11:38:42）

Shibahara Hiroaki
Department Specialty Division Obstetrics and Gynecology, Clinical Medicine Seminars

Position

■ Journal

1.	Introduction	Methods for direct and indirect antisperm antibody testing 2013/01
2.	Case report	Long-term disease-free survival after radical local excision of low-grade myofibroblastic sarcoma of the vulva. 2013/04
3.	Case report	A case of primary metastatic glassy cell carcinoma of the uterine cervix that responded to combined docetaxel and carboplatin. 2013/07
4.	Original article	Live births from isolated primary/early secondary follicles following a multistep culture without organ culture in mice. 2013/07
5.	Original article	Prognostic factors for locally advanced cervical cancer treated with neoadjuvant intravenous and transuterine arterial chemotherapy followed by radical hysterectomy 2013/10
6.	Original article	Development of an integrated support system for hereditary cancer and its impact on gynecologic services. 2013/12
7.	Original article	Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males 2013/12
8.	Introduction	Infertility and immunocontraception based on zona pellucida. 2014/01
9.	Original article	Benefit of palliative chemotherapy and hospice enrollment in late-stage ovarian cancer patients. 2014/05
10.	Original article	Feasibility and efficacy of intraperitoneal docetaxel administration as salvage chemotherapy for malignant gynaecological ascites. 2014/07
11.	Original article	Expression of Chemokine Ligand 18 in Stage IA Low-grade Endometrial Cancer. 2014/10
12.	Case report	Complete remission achieved by oophorectomy for recurrent endometrial stromal sarcoma after laparoscopic morcellation. 2014/11
13.	Original article	Development of an integrated support system for hereditary cancer and its impact on gynecologic services. 2014/12
14.	Original article	Methylation progress of mouse maternal imprinted gene, LIT1 and Zac1 in primary follicles under in-vitro conditions. 2015/02
15.	Original article	Mitochondrial DNA copy number in cumulus cells is a strong predictor of obtaining good-quality embryos after IVF 2015/12
16.	Case report	Bevacizumab helped resolve pericardial and pleural effusion that was associated with malignant ovarian clear cell carcinoma 2016/01
17.	Original article	Expression of Hedgehog Signals and Growth Inhibition by Itraconazole in Endometrial Cancer 2016/01
18.	Original article	Gremlin 2 is Repressed in Invasive Endometrial Cancer and Inhibits Cell Growth In Vitro 2016/01
19.	Case report	Pazopanib-mediated long-term disease stabilization after resection of a uterine leiomyosarcoma metastasis 2016/01
20.	Research report	The present status of certified"embryologists of assisted reproductive technology" in Japan 2015 2016/04
21.	Original article	Effects of gremlin-2 on the transition of primordial follicles during early folliculogenesis in the human ovary 2016/05
22.	Original article	Itraconazole Inhibits AKT/mTOR Signaling and Proliferation in Endometrial Cancer Cells. 2017/02
23.	Introduction	Repurposing itraconazole as an anticancer agent (Review) 2017/04
24.	Original article	Quantitative and qualitative changes of mitochondria in human preimplantation embryos 2017/05
25.	Original article	Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells 2017/07
26.	Original article	Fertility Preservation for Adolescent and Young Adult Women in Hyogo College of Medicine College Hospital 2017/09
27.	Original article	Expression of natural cytotoxicity receptors and cytokine production on endometrial natural killer cells in women with recurrent pregnancy loss or implantation failure, and the expression of natural cytotoxicity receptors on peripheral blood natural killer cells in pregnant women with a history of recurrent pregnancy loss. 2017/11
28.	Introduction	The current perspectives on the mammalian zona pellucida. 2017/12
29.	Case report	A Case of a Pregnant Woman with Thrombosis in an Artificial Aortic Valve Resulting in Severe Cerebral Hemorrhage in the Newborn 2018/01
30.	Case report	Pazopanib treatment of a platinum-resistant recurrence of a high-grade Sertoli cell tumor and assessment of the treatment response by FDG-PET/CT: A case report 2018/01
31.	Original article	Status of ovarian tissue cryopreservation for adolescent and young adult patients with cancer in Hyogo College of Medicine College Hospital. 2018/01
32.	Case report	Adolescent bladder endometriosis initially diagnosed as premenarchal disease: a case report and review of the literature 2018/03
33.	Case report	Bevacizumab with metronomic chemotherapy of low-dose oral cyclophosphamide in recurrent cervical cancer: Four cases 2018/04
34.	Original article	Fertility preservation and pregnancy outcomes in adolescent and young adult male patients with cancer. 2018/10
35.	Original article	Effects of leuprorelin for the treatment of recurrent gynecological cancer by assessment including self-administered quality-of-life questionnaire 2019/01
36.	Case report	Resuscitative hysterotomy in a patient with peripartum cardiomyopathy 2019/03
37.	Case report	Removal of a Retroperitoneal Foreign Body by Laparoscopic Surgery. 2019/04
38.	Original article	Challenges in Managing Patients with Hereditary Cancer at Gynecological Services 2019/05
39.	Original article	Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis. 2019/08
40.	Case report	Association Between Spontaneous Ovulation and Serum anti-Müllerian Hormone Levels in a Premature Ovarian Insufficiency Patient After a Multimodal Treatment for Breast Cancer 2019/11
41.	Original article	Effects of 5-hydroxytrypyamine on spermatozoal hyperactivation and in vitro fertilization in mice. 2019/11
42.	Original article	Paternal occupational exposure to chemicals and secondary sex ratio: results from the Japan Environment and Children's Study. 2019/12
43.	Original article	Mitochondrial oxygen consumption rate of human embryos declines with maternal age 2020/09
44.	Original article	Prevention and practice during the COVID-19 emergency declaration period in Japanese obstetrical/gynecological facilities 2020/09
45.	Introduction	Anti-sperm antibodies and reproductive failures 2021/04
46.	Original article	Co-expression of NKp46 with activating or inhibitory receptors on, and cytokine production by, uterine endometrial NK cells in recurrent pregnancy loss 2021/04
47.	Original article	Pelvic endometriosis and natural killer cell immunity 2021/04
48.	Original article	Association between the serum insulin-like growth factor-1 concentration in the first trimester of pregnancy and postpartum depression 2021/05
49.	Original article	Association between the serum insulin-like growth factor-1 concentration in the first trimester of pregnancy and postpartum depression. 2021/05
50.	Original article	Sperm immobilization test and quantitative sperm immobilization test using frozen-thawed sperm preparation applied with computer-aided sperm analysis 2021/05
51.	Case report	The chronological change in transvaginal ultrasound images of a hemorrhagic ovarian cyst observed during infertility treatment: A case report and literature review 2021/07
52.	Original article	Feelings about pregnancy and mother-infant bonding as predictors of persistent psychological distress in the perinatal period: The Japan Environment and Children's Study. 2021/08
53.	Original article	Itraconazole increases resolvin E3 concentration and 12/15-lipoxygenase inhibitor attenuates its anticancer activity in cervical cancer cells 2021/09
54.	Original article	NK cells that differ in expression of NKp46 might play different roles in endometrium 2021/09
55.	Original article	Itraconazole Inhibits Intracellular Cholesterol Trafficking and Decreases Phosphatidylserine Level in Cervical Cancer Cells 2021/11
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■ BooK

Contributor　

Sperm Immobilizing Antibody and Its Target Antigen, Immune Infertility 2017/01

■ Presentation

1.	Identification of a novel sperm-specific protein reacted with sperm-immobilizing antibody from immunologically infertile men. 2013/05/28
2.	A case of fetal hypothyroidism recognized during treatment of Basedow disease with oral medicine 2013/06/02
3.	Benefit of palliative chemotherapy and hospice enrollment in late-stage ovarian cancer patients 2013/10/19
4.	Prognostic factors for cernical cancer treated with neoadjuvant trans-uterine arterial chemotherapy: A single-institution study 2013/10/19
5.	Infertile women with lower AMH value due to past history of ovarian surgery have higher chance of successful pregnancy by ART. 2013/10/21
6.	Evaluation of the gene expression involved in implantation 2013/12/01
7.	Succesful live births from primary or early secondary follicles through multistep in-vitro growth (IVG) followed by in-vitro fertilization and embryo transfer (IVG-ET) in mice 2013/12/01
8.	Evaluation of the gene expression in peripheral endometrial carcinoma tissue. 2014/05/01
9.	Role of anti-sperm antibodies in immunologically infertile women 2014/05/23
10.	Development of GVHD therapy using fetal appendage derived MSCs 2015/03/06
11.	Expression and localization of hormone receptors and growth factors in the ovarian sections from cynomogus monkeys 2015/04/26
12.	ICSI in not necessary for the treatment of immunologically infertile women with sperm immobilizing antibodies 2015/04/26
13.	Indvidualized controlled ovarian stimulation (iCOS)and luteal support for ART 2015/04/26
14.	Management and complications of pregnancies after egg donation in our hosptal 2015/04/26
15.	Immunocytochemical study of ovarian hormone receptors and factors in non-human primate (Macaca Fascicularis) 2015/05/22
16.	Profiling of gene expression during early folliculogenesis in mice. 2015/05/22
17.	Expression of Hedgehog signals and growth inhibition by itraconazole in endomertial 2016/04/16
18.	Gremlin2 is repressed in invasive endometrial cancer and inhibits cell growth in vitro 2016/04/16
19.	A three year experience of fertility preservation for AYA women 2016/05/21
20.	Presence and possible function of Gremlin2 in the human ovary 2016/05/21
21.	Analysis of sperm immobilization by complement-dependent sperm immobilizing antibody using computer-aided sperm analysis (CASA) 2016/06/22
22.	The role of seminal vesicle fluid on successful embryo implantation for IVF-ET system in mice 2016/06/22
23.	The Status of Sperm Immobilizing-Antibody (SI-Ab) detected in Infertile Females (Therapy and Pathogenic Mechanisms) 2016/06/22
24.	Repositioning itraconazole as an anticancer drug for endometrial cancer 2016/07/09
25.	Analysis of four cases of unexpected NIPT results; false positive, false-negative and non-reportable cases 2016/07/10
26.	Radiographic pelvimetry: evaluation of radiation dose and image quality 2016/07/10
27.	Development of a safe and effective cryoprotectant for ovarian cryopreservation 2016/11/18
28.	Experience of fertility preservation in male cancer patients 2016/11/18
29.	Fertility preservation for adolescent and young adult women 2016/11/18
30.	A fetus with lethal chromosomal abnormality lead to a spontaneous abortion in the first trimester 2017/06/15
31.	Development of a regional oncofertility network for fertility preservation in AYA patients: one-year experience 2017/06/15
32.	Possible molecular mechanism for infertility in women caused by sperm immobilizing antibody(Sl-Ab) 2017/09/07
33.	A strategy for the treatment of infertile woman with sperm immobilizing antibody in their sera 2017/09/17
34.	Application of computer-aided sperm analysis (CASA)for detecting sperm immobilizing antibody 2017/09/17
35.	NK cells and reproduction our progress in NK cell study 2017/09/17
36.	The co-expression of activating and inhibitory receptors and cytokines production for uterine NK cells 2017/09/17
37.	Regulation of rodent sperm hyperactivation by serotonin 2017/09/28
38.	Fertility preservation in male AYA patients with cancer 2017/10/14
39.	A successful pregnancy in a patient with 46,XY pure gonadal dysgenesis after transfer of a frozen-thawed embryo derived from donor oocytes 2018/05/11
40.	Application of Compute-Aided Sperm Analysis (CASA) for Sperm Immobilization Test 2018/05/11
41.	Fertility preservation by ovarian tissue cryopreservation for adolescent and young adult patients in our department 2018/05/11
42.	Repurposing itraconazole as an anticancer agent : rapid clinical response of metastatic vaginal melanoma 2018/05/11
43.	Vulvar apocrine adenocarcinoma responded to weekly paclitaxel and biweekly bevacizumab. A case report 2018/05/11
44.	NK cell abnormality and its treatment in women with reproductive failure 2018/06/15
45.	Successful pregnancy in a case of repeated implantation failure(RIF) due to elevated Th1/Th2 using intravenous immunoglobulin treatment(IVIG) 2018/06/28
46.	The co-expression of activating and inhibitory receptors and cytokines production for uterine NK cells 2018/06/28
47.	Cytokaines production and co-expression of activating and inhibitory receptors of uterine NK cells in RPL 2019/06/11
48.	Mouse ovarian culture using meshes and evaluation of follicular development 2019/10/24
49.	Cytokines production and co-expression of activating and inhibitory receptors of uterine NK cells in woman with RPL 2019/11/13
50.	His research on anti-sperm antibody 2019/11/13
51.	In regards to different density of CD16 on NK cells, are they play different role in reproductive outcome? 2019/11/13
52.	The expression of NKp46 on uterine NK cells and Cytokines Production by NK cells in women with recurrent Pregnancy loss 2019/11/13
53.	Do NKp46^dim and NKp46^bright receptors play different role in reproduction? 2020/04/24
54.	Genomic profiling of primary peritoneal cancer with platinum sensitive recurrence. A two cases 2020/04/24
55.	The chronological change of the transvaginal ultrasound images of a hemorrhagic ovarian cyst 2020/04/24
56.	The precise ovarian volume is significantly associated with circulating levels of AMH, the ratio of LH/FSH and total testosterone concentrations 2020/04/24
57.	Metronomic chemotherapy using oral cyclophosphamide and bevacizumab (mCPA-BEV) for recurrent cervical cancer 2020/04/25
58.	A long-team response to olaparib in a germline BRCA mutated patient with uterine serous carcinoma : A case report 2020/04/26
59.	CO-EXPRESSION OF ACTIVATING AND INHIBITORY RECEPTORS ON PERITONEAL FLUID NK CELLS IN WOMEN WITH ENDOMETRIOSIS. 2020/10/17
60.	Characterization of spontaneously occurred IgA antibody against sperm 2021/04/10
61.	Our challenge to increase the success rate for hysteroscopically assisted falloposcopic tuboplasty 2021/04/24
62.	Anti-Mullerian hormone (AMH) as an ovarian reserve marker in cancer patients who undergo ovarian tissue cryopreservation 2021/04/25
63.	Bevacizumab with metronomic oral cyclophosphamide for patients with recurrent cervical cancer 2021/04/25
64.	In regards to different fluorescence density of NKp46 on NK cells, are they play different role in reproductive outcome? 2021/04/25
65.	Rapid response to itraconazole and transcript analysis of the cervical cancer tissue obtained by the sequential biopsy: A case report 2021/04/25
66.	Resolvin E3 : The mechanism of anti-cancer effect of itraconazole in cervical cancer 2021/04/25
67.	Co-expression of activating and inhabitory receptors on peritoneal fluid NK cells in women with endometriosis 2021/05
68.	The roles of NKp46 and CD16 on NK cells in reproduction 2021/05
69.	Fertility preservation in an infant with cerebellar medulloblastoma 2021/09/11
70.	Reproductive outcome of septate uterus after hybrid hysteroscopic metroplasty 2021/09/11
71.	Safe and affective hysteroscopically and fluoroscopically assisted falloposcopic tuboplasty for women with tubal infertility 2021/09/12
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