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Journal
Presentation
    （Last updated : 2021-05-27 15:52:15）
  Goto Akinobu
   Department   Specialty Division  , Basic Medicine Subject
   Position  
■ Journal
1. Original article　 A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression. 2013/01
2. Original article　 Naftopidil induces apoptosis in malignant mesothelioma cell lines independently of α1-adrenoceptor blocking. 2013/03
3. Original article　 Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis. 2013/04
4. Original article　 Potential tumor markers of renal cell carcinoma: α-enolase for postoperative follow up, and galectin-1 and galectin-3 for primary detection. 2013/05
5. Original article　 DL-/PO-phosphatidylcholine may shed light on the treatment of Alzheimer dementia. 2013/07
6. Original article　 DL-/PO-phosphatidylcholine serves as a memory enhancer for normal healthy subjects. 2013/07
7. Original article　 Crosstalkbetween PI3 kinase/PDK1/Akt/Rac1 and Ras/Raf/MEK/ERK pathways downstream PDGF receptor. 2013/10
8. Original article　 Newly synthesized anticancer drug HUHS1015 is effective on malignant pleural mesothelioma. 2014/07
9. Original article　 Naftopidil Is Useful for the Treatment of Malignant Pleural Mesothelioma 2014/10
10. Original article　 Adenosine Deaminase Inhibitor EHNA Exhibits a Potent Anticancer Effect Against Malignant Pleural Mesothelioma 2015/01
11. Introduction　 Cancer stem cell markers in lung cancer. 2015/07
12. Introduction　 Repositioned alpha-1 adrenoceptor blockers as anti-tumor drugs. 2015/07
13. Original article　 Piperazine-based alpha-1 AR blocker, naftopidil, selectively suppresses malignant human bladder cells via induction of apoptosis. 2016/04
14. Introduction　 Discussion of current ethical issues regarding the use of assisted reproductive treatment in Japan. 2016/06
15. Original article　 The phosphatidylethanolamine derivative diDCP-LA-PE mimics intracellular insulin signaling. 2016/06
16. Original article　 The Clinical Significance of Cancer Stem Cell Markers ALDH1A1 and CD133 in Lung Adenocarcinoma. 2017
17. Original article　 Autophagy induced by naftopidil inhibits apoptosis of human gastric cancer cells. 2018/02
18. Original article　 Lentiviral Vector-Mediated Gene Transfer in Human Bladder Cancer Cell Lines. 2018/04
19. Original article　 Lentiviral vector-mediated gene transfer combined with cisplatin enhances tumor suppression in human bladder cancer cell lines. 2019/07
20. Original article　 Lentiviral vector-mediated transfection of p53, p16 and PTEN genes against human renal cell carcinoma cell lines. 2019/07
21. Original article　 Identification of HUHS190, a human naftopidil metabolite, as a novel anti-bladder cancer drug. 2020/01
22. Original article　 Cancer stem cell markers in lung adenocarcinoma. 2020/12
23. Original article　 Lentiviral vector-mediated transfection of human cancer cell lines with tumor suppressor genes inhibits proliferation in vitro. 2020/12
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■ Presentation
1. Consumption of oxygen:A mitochondrial-generated progression signal of advanced cancer.  2013/05/06
2. Oncolytic effects of a fiber knob substituted adenovirus vector to human lung cancer cells.  2013/07/05
3. Antitumor Effect of Alpha1-Adrenoceptor Blockers on Human Urological Cancer Cells.  2013/10/03
4. Crosstalk between ERK and Akt pathways in malignant mesothelioma cells.  2013/10/03
5. Sonic hedgehog and androgens signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer.  2014/09/06
6. Evaluations of Aldehyde dehydrogenase-1 (ALDH1) immunoreactivity in human lung adenocarcinoma.  2014/09/25
7. Expression of Aldehyde dehydrogenase-1 (ALDH1) and its relationship with clinical parameters in lung adenocarcinoma.  2014/09/25
8. Development of the newly anticancer drug for human bladder cancer.  2014/09/26
9. Salvianolic acid B suppresses growth of malignant pleural mesothelioma.  2014/09/26
10. Newly synthesized anticancer agent HUHS1015(naftopidil analogue) is effective for malignant pleural mesothelioma(MPM).  2014/10/22
11. A drug repositioning approach identifies alpha-1 blockers as drugs of bladder cancer.  2015/03/27
12. Cancer stem cell marker (ALDH1 expression) and its relationship with clinicopathological parameters in lung adenocarcinoma.  2015/04/18
13. Corrrelation of cancer stem cell marker (ALDH1) and molecular tumor markers (EGFR, K-ras, p53) in lung adenocarcinoma  2015/04/18
14. Potent Anti-Mesothelioma Activity by the Novel Naftopidil Analogue HUHS1015,Preclinical Evidence for Treatment.  2015/09/08
15. Naftopidil Is Effective in the Treatment of Malignant Pleural Mesothelioma.  2015/09/09
16. Development of the new anti-cancer drug using drug repositioning methods.  2015/10/09
17. Cancer stem cell markers (ALDH1 and CD133) expression could be associated with a poor prognosis in the patients with lung adnocarcinoma.  2016/04/19
18. Clinical significance of cancer stem cell markers (ALDH1 and CD133) in the patients with lung adenocarcinoma.  2016/10/06
19. Danshen suppresses growth of malignant pleural mesothelioma.  2016/10/06
20. Evaluations of aldehyde dehydrogenase-1 (ALDH1) and TP53 expressions in human lung adenocarcinoma.  2016/10/06
21. Antitumor effect of naftopidil against undifferentiated gastric cancer cells.  2016/10/07
22. Expressions of aldehyde dehydrogenase-1 (ALDH1) and TP53 in human lung adenocarcinoma.  2017/04/28
23. Evaluations of aldehyde dehydrogenase-1 (ALDH1) and CD133 expressions in human lung adenocarcinoma.  2017/09/28
24. Naftopidil induces autophagy in undifferentiated gastric cancer cells.  2017/09/30
25. Expressions of aldehyde dehydrogenase-1 (ALDH1) and CD133 in human lung adenocarcinoma.  2018/04/07
26. Lentiviral vector-mediated gene transfer in bladder cancer cells.  2018/09/28
27. Relationships between cancer stem cell markers (ALDH1 & CD133) and disease-free intervals in human lung adenocarcinoma.  2018/09/29
28. Expressions of cancer stem cell markers (ALDH1 & CD133) and those disease-free intervals in human lung adenocarcinoma.  2019/04/18
29. Expressions of cancer stem cell markers (ALDH1 & CD133) and those disease-free intervals (DFI) and survivals in human lung adenocarcinoma.  2019/05/16
30. Expressions of cancer stem cell markers (ALDH1 & CD133) and evaluations of those disease-free intervals (DFI) and survivals in human lung adenocarcinoma.  2019/05/23
31. Combined effect of Lentiviral vector mediated gene transfer and cisplatin.  2019/07/22
32. Lentiviral vector mediated transfection of tumor suppressor genes.  2019/07/22
33. Evaluations of aldehyde dehydrogenase-1 (ALDH1), CD133 and CD44 expressions in human lung adenocarcinoma.  2019/09/27
34. Lentiviral vector-mediated transfection of tumor suppressor genes in human c ancer cell lines.  2019/09/27
35. Expression of Cancer Stem Cell markers in human lung adenocarcinoma.  2019/10/20
36. Gene transfection against bladder cancer cell line using lentiviral vectors.  2019/10/20
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